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Apigenin

12 Inquiries

Unit Price: Get Latest Price
CAS No.:

520-36-5

Grade:

Food Grade

Content:

98%

Port:

SHANGHAI

Brand:

Benepure

Packaging:

25kg/Cardboard Drum

Price valid (until):

2022-08-11

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Neohesperidin Dihydrochalcone,Baicalin,Cephalotaxine,Diosmin,Naringin,Cranberry Extract

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Product Name: Apigenin
    Synonym: Eriodictyl-7-Rutinoside
    CAS Number: 520-36-5
    Specification:95% 98%HPLC
    Appearance: Yellowish brown fine powder
    Botanical Source: Citrus aurantium L.

    Description:
    Belonging to the flavone class, which is the aglycone of several naturally occurring glycosides, apigenin can be found in many plant. When it is dried and purified, its form is yellow powder.
    Apigenin exist in many plant, but the main source is celery, celeriac, and chamomile.

    Application:
    By series of vitro experiments and studies in animal, apigenin approved to be a variety of potential biological activities, but its effects on human body is still under developed.
    Apigenin induces autophagy (a kind of cellular waste-recycling system) in leukemia cells, which may support a possible chemopreventive role, but that induction of autophagy simultaneously induces resistance against the chemotherapy drug vincristine. Apigenin is a potent inhibitor of CYP2C9, an enzyme responsible for the metabolism of many pharmaceutical drugs in the body.
    When performance an experience in animal, apigenin has been shown to prevent renal damage caused by cyclosporine in rats, associated with reduce expression of the cell death mediator bcl-2 in histopathological sections. Cyclosporine A enhances the expression of transforming growth factor-β in the rat kidney, which signifies accelerated apoptosis. Therefore, transforming growth factor-β and apoptotic index may be used to assess apigenin and its effect on cyclosporine A-induced renal damage.

    Basic Info
    Product Name:

    Apigenin

    Other Name:

    4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(4-hydroxyphenyl)-;Flavone,4′,5,7-trihydroxy-;5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;Apigenin;Chamomile;C.I. Natural Yellow 1;4′,5,7-Trihydroxyflavone;Apigenine;Apigenol;5,7,4′-Trihydroxyflavone;LY 080400;UCCF 031;Pelargidenon 1449;Apegenin;Versulin;NSC 83244;5,7-Dihydroxy-2-(4-hydroxyphenyl)chromen-4-one;5,7-Dihydroxy-2-p-hydroxyphenyl-4-chromenone;ST 056301;461015-54-3

    CAS No.:

    520-36-5

    Molecular Formula:

    C15H10O5

    InChIKeys:

    InChIKey=KZNIFHPLKGYRTM-UHFFFAOYSA-N

    Molecular Weight:

    270.23700

    Exact Mass:

    270.24

    EC Number:

    926-224-7

    UNII:

    7V515PI7F6

    NSC Number:

    83244

    DSSTox ID:

    DTXSID6022391

    Color/Form:

    Yellow needles from aqueous pyridine

    HScode:

    2942000000

    Characteristics
    PSA:

    90.90000

    XLogP3:

    1.7

    Appearance:

    Solid

    Density:

    1.548 g/cm3

    Melting Point:

    347.5 °C

    Boiling Point:

    555.5ºC at 760 mmHg

    Flash Point:

    217ºC

    Refractive Index:

    1.732

    Water Solubility:

    DMSO: 27 mg/mL;In water, 183 mg/L at 25 deg C (est)

    Storage Conditions:

    -20ºC

    Vapor Pressure:

    1.01X10-10 mm Hg at 25 deg C (est)

    Henrys Law Constant:

    Henry's Law constant = 5.12X10-17 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa1 = 7.12 (phenol); pKa2 = 8.10 (phenol) (est)

    Collision Cross Section:

    156 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 2.31X10-10 cu cm/molec-sec at 25 °C (est)|Ozone reaction rate constant = 1.05X10-16 cu cm/molec sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Neohesperidin Dihydrochalcone,Baicalin,Cephalotaxine,Diosmin,Naringin,Cranberry Extract

    Location:

    99# Jirui 3rd Road, High-tech District,Chengdu, Sichuan Prov., China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A

    Average lead Time:

    7

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    101-200

    Year of Establishment:

    2004

    Certifications:

    The registered trademark of company,The registered trademark of product

    Sichuan Benepure Pharmaceutical Co.,Ltd. is a professional manufacturer and research institution, serving the pharmaceutical, veterinary, cosmetics, natural foods and animal nutrition industries by providing a diverse range of over 300 unique beneficial ingredients, headquartered in China(Sichuan) Free Trade Area. 


    Benepure prides itself on manufacturing system standard above the GMP certification of many countries, meeting exact demands of various international regulations. Benepure is now manufacturing and supplying over 300 products of unsurpassed quality and maintaining two plants in China.


    Benepure is dedicated to the reduction of emission pollution and environmental protection during the manufacturing process for long-term sustainability of social and economic development. 

  • Inquiry History
    12 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    98% Apigenin powder

    10 KG Sep 4, 2024
    France

    Apigenin

    10 KG Oct 24, 2025
    Vietnam

    Chamomile Extract 98% apigenin powder

    120 KG Jan 10, 2024
    Germany

    Professional manufacturer supply Citrus grandis (L.) Osbeck extract Apigenin 98%

    40 MT Oct 25, 2023
    India

    Apigenin

    1.00 KG Mar 2, 2026
    India

    apigenin powder 98%

    1 KG Jan 19, 2026
    Indonesia

    APIGENIN

    500 G Nov 21, 2025
    United States

    Apigenin

    4000 KG Oct 10, 2024
    Mexico

    Apigenin

    10 G Sep 21, 2024
    India

    Apigenin

    10 G May 22, 2026
    Australia

    Apigenin

    1 KG Nov 15, 2024
    Chile

    Apigenin

    25 KG Mar 26, 2024
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