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Aptinib CAS No.811803-05-1

Name: Aptinib CAS No.811803-05-1
Brand: JINLAN PHARM
SKU: pr2209062224
Price: 10 USD
Availability: InStock

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CAS No.:

811803-05-1

Grade:

Pharmaceutical grade

Content:

99%

Port:

Shanghai

Brand:

JINLAN PHARM

Packaging:

25Kg/drum

Price valid (until):

2022-12-31

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ROYAL PHARM

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

30 days

Qualification:

Main Products:

additives,pharmaceutical chemicals,organic intermediate,chemical intermediates,Pharmaceutical Intermediates,catalyst

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Product Description
Seller Information

Description

Quick Details:
Name:Aptinib

CAS No.:811803-05-1

lace of Origin: China (Mainland)
Grade Standard: Pharmaceutical Grade
Brand Name: JINLAN PHARM
We recommend T/T or Escrow , D/P,D/A,or PayPal are also acceptable!

Delivery:
In about 3 working days after the receipt of payment, we will follow up the delivery until you receive it.
Express way as the following is:
(Shipping : TNT, Fedex, DHL,USP,EMS and so on)

(By air,by sea,by rail...)

Packaging:
Drum & plastic bags, Aluminum foiled bag, Zip lock bags
Our Company:
Our company advantage:
1.Small order is acceptable
2.Can provide sample for you
3.Have self-export rights

The End

CONTACT US:

Jinlan Pharm-Drugs Technology Co., Limited

Hangzhou Royall Import & Export Co.,Ltd.

Add:Room 1701, Building 3, Greenland Central Plaza, No.98 Daguan Road, Gongshu District, Hangzhou

Tel: 0086-571-86982637-8201 Fax: 0086-571-86982637

WhasAPP:+86 18258187294 Wechat:18258187284

Email : sales07@royalpharms.com

http://www.jlpharms.com/---Jinlan Pharm

http://www.royalpharms.com/ --- Royal Pharm

http://www.royal-hz.com/ --- Royal Agency

ECHEMI Editorial Reference

Apatinib free base (YN968D1 free base) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 (IC50=1 nM). Apatinib free base (YN968D1 free base) is an anti-angiogenic drug for the treatment of advanced or metastatic gastric cancer. Apatinib free base (YN968D1 free base) potently inhibits Ret, c-Kit and c-Src with IC50s of 13, 429 and 530 nM, respectively. It also inhibits cellular phosphorylation of VEGFR-2, c-kit and PDGFRβ[1][2][3].
Rivoceranib is under investigation in clinical trial NCT02726854 (Apatinib as Second-line Treatment of Advanced Pancreatic Cancer).|Rivoceranib is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Upon administration, rivoceranib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.

Basic Info

Product Name:

N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide

Other Name:

3-Pyridinecarboxamide,N-[4-(1-cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-;N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide;Rivoceranib;N-[4-(1-cyanocyclopentyl)phenyl]-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide;YN 968D1;1275609-09-0

CAS No.:

811803-05-1

Molecular Formula:

C24H23N5O

InChIKeys:

InChIKey=WPEWQEMJFLWMLV-UHFFFAOYSA-N

Molecular Weight:

397.47232

Exact Mass:

397.47

EC Number:

1592732-453-0

UNII:

5S371K6132

DSSTox ID:

DTXSID80153427

NCI Thesaurus Code:

C152237

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

90.7

Density:

1.3±0.1 g/cm3

Boiling Point:

578.2°C at 760 mmHg

Flash Point:

303.5±30.1 °C

Refractive Index:

1.652

See More N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
additives,pharmaceutical chemicals,organic intermediate,chemical intermediates,Pharmaceutical Intermediates,catalyst

Location:
hangzhou,zhejiang

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
30 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2020

ROYAL PHARM is a leading Trader supplier of Everolimus, Doramectin, Topiramate based in Hangzhou, Zhejiang, China. With a commitment to quality and customer satisfaction, ROYAL PHARM has become a trusted name in the industry. Our product line includes a range of high-quality Everolimus, Doramectin, Topiramate, which are available at competitive prices. ROYAL PHARM has established itself as a reliable supplier of chemical products on the echemi.com.
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Aptinib CAS No.811803-05-1

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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