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Fluorocytosine

HALAL KOSHER ISO FDA

Unit Price: Get Latest Price
CAS No.:

2022-85-7

Grade:

Pharmaceutical grade

Content:

0.99%

Packaging:

1KG;25KG;private logo

Price valid (until):

2023-09-01

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Herb Extracts,Cosmetic raw materails,API

  • Product Description

  • Seller Information

  • Description


      Fluorocytosine  


    • Introduction:5-fluorocytosine (5-FC) is also called fluorocytosine, 5-fluorocytosine, Anquzhi, Allah spray, white or white crystalline powder. The inhibitory effect of 5-flucytosine ON FUNGI IS due to its entry into the cells of sensitive fungi, and under the action of cytosine deaminase, the amino group is removed and the anti-metabolite 5-fluorouracil is formed. The latter in turn transforms into 5-fluorouracil deoxynucleoside and inhibits thymidine nucleoside synthetase, blocks the transformation of uracil deoxynucleoside into thymidine nucleoside, and affects DNA synthesis. It has good inhibitory effect on Candida, Cryptococcus and Trichoderma. It also has effect on some Aspergillus, as well as the mycospores and bottle fungi that cause skin mycosis.
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    Basic Info
    Product Name:

    Flucytosine

    Other Name:

    2(1H)-Pyrimidinone,6-amino-5-fluoro-;2(1H)-Pyrimidinone,4-amino-5-fluoro-;Cytosine,5-fluoro-;6-Amino-5-fluoro-2(1H)-pyrimidinone;5-Fluorocytosine;Flucytosine;4-Amino-5-fluoropyrimidin-2(1H)-one;5-Fluorocytosin;Flucytosin;Ro 2-9915;Fluocytosine;Ancobon;Fluorocytosine;Ancotyl;Ancotil;6-Amino-2-oxo-5-fluoropyrimidine;Alcobon;NSC 103805;4-Amino-5-fluoropyrimidin-2-ol;Toca FC

    CAS No.:

    2022-85-7

    Molecular Formula:

    C4H4FN3O

    InChIKeys:

    InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N

    Molecular Weight:

    129.09

    Exact Mass:

    129.09

    BRN:

    127285

    EC Number:

    217-968-7

    UNII:

    D83282DT06

    NSC Number:

    759130|103805

    DSSTox ID:

    DTXSID3023059

    NCI Thesaurus Code:

    C501

    Color/Form:

    White crystalline solid

    ATC Code:

    D - Dermatologicals|J - Antiinfectives for systemic use

    HScode:

    2933599090

    Characteristics
    PSA:

    67.5

    XLogP3:

    -1.1

    Appearance:

    White to almost white Crystalline Powder

    Density:

    1.7±0.1 g/cm3

    Melting Point:

    295-297 °C (decomp)

    Refractive Index:

    1.649

    Water Solubility:

    H2O: 1.5g/100mL (25 ºC)

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    4.5X10-6 mm Hg at 25 °C (est)

    Toxicity:

    LD50 in mice (mg/kg): >2000 orally and s.c.; 1190 i.p.; 500 i.v. (Grunberg, 1963)

    Odor:

    Odorless

    PKA:

    3.26None

    Henrys Law Constant:

    Henry's Law constant = 9.21X10-11 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    3.26|pKa1 = 3.26; pKa2 = 10.71

    Collision Cross Section:

    118.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    Aqueous solutions, both acidic and basic, are stable.|Hydroxyl radical reaction rate constant = 1.19X10-11 cu cm/molec-sec at 25 °C (est)|Ozone reaction rate constant = 7.0X10-19 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    capsules should be stored in tight, light-resistant containers at a temperature less than 40 deg C, preferably at 15-30 deg C.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Herb Extracts,Cosmetic raw materails,API

    Location:

    1403,Jinye B Block

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    8

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    11-50

    Year of Establishment:

    2015

    Xian ZB Biotech Co.,Ltd is a leading Manufactory supplier of Arbutin, Nicotinamide, Flucytosine based in Xi'an, Shaanxi, China. With a commitment to quality and customer satisfaction, Xian ZB Biotech Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Arbutin, Nicotinamide, Flucytosine, which are available at competitive prices. Xian ZB Biotech Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

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