Native Bacillus sp. Purine Nucleoside Phosphorylase
9030-21-1
2026-10-07
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Native Bacillus sp. Purine Nucleoside Phosphorylase Cat No DIA-164 Description Purine nucleoside phosphorylase (also known as PNPase) is an enzyme (EC 2.4.2.1) involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine, in each case creating ribose phosphate. NP encodes the enzyme purine nucleoside phosphorylase that together with adenosine deaminase (ADA) serves a key role in purine catabolism, referred to as the salvage pathway. Mutations in either enzyme result in a severe combined immunodeficiency (SCID). Confusingly, the same abbreviation (PNPase), is also used for another, otherwise unrelated, enzyme, namely Polynucleotide Phosphorylase. Abbr PNPase (Bacillus sp.) Alias PNPase; PUNPI; PUNPII Source Bacillus sp. Applications Useful for enzymatic determination of inorganic phosphate Appearance Colourless to light brown solution Product Overview Purine Nucleoside Phosphorylase produced in microorganism has a molecular mass of 32 kDa. Form Liquid Enzyme Commission Number EC 2.4.2.1 Activity > 500U/mL CAS No 9030-21-1 Contaminants NADH oxidase < 0.002% pH Stability 6.0-10.0 (37°C (Tris-HCI buffer) Optimum pH 8 Thermal stability Stable at 65°C and below (pH 8.5, 10 mins) Storage -20°C Inhibitors Ag+, Hg2+ Pathway Nicotinate and nicotinamide metabolism; Purine metabolism; Pyrimidine metabolism; Nucleotide metabolism. Function purine-nucleoside phosphorylase activity; purine-nucleoside phosphorylase activity; purine-nucleoside phosphorylase activity. Synonyms inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynucleoside phosphorylase; purine deoxyribonucleoside phosphorylase; purine nucleoside phosphorylase; purine ribonucleoside phosphorylase; purine-nucleoside: phosphate ribosyltransferase; EC 2.4.2.1 category Enzyme(c2117) cas_num 9030-21-1 ECHEMI Editorial ReferencePowderBasic Info-
Product Name:
Purine nucleoside phosphorylase
Other Name:Purine nucleoside phosphorylase;Phosphorylase,purine nucleoside;E.C. 2.4.2.1;Inosine phosphorylase;Purine ribonucleoside phosphorylase;Purine deoxyribonucleoside phosphorylase;Inosine-guanosine phosphorylase;Nucleotide phosphatase (2.4.2.1);Purine deoxynucleoside phosphorylase;Deoxyribonucleoside phosphorylase
CAS No.:9030-21-1
InChIKeys:MRWXACSTFXYYMV-FDDDBJFASA-N
Molecular Weight:252.22668
Exact Mass:143.025024
EC Number:232-857-3
HScode:35079090
Categories:
Characteristics-
PSA:
64.93000
XLogP3:1.09
Appearance:lyophilized powder
Density:1.4±0.1 g/cm3
Melting Point:181
Boiling Point:409.3±40.0 °C at 760 mmHg
Flash Point:201.3±27.3 °C
Refractive Index:1.685
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
Respiratory sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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