Native Streptomyces sp. Cholesterol Oxidase
1 Inquiries
9028-76-6
2026-07-27
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Native Streptomyces sp. Cholesterol Oxidase Cat No NATE-0128 Description Cholesterol oxidase (CHOD) is a monomeric flavoprotein containing FAD that catalyzes the first step in cholesterol catabolism. This bifunctional enzyme oxidizes cholesterol to cholest-5-en-3-one in an FAD-requiring step, which is then isomerized to cholest-4-en-3-one with the release of H2O2. Abbr CHOD, Native (Streptomyces sp.) Alias CHOD Source Streptomyces sp. Applications Cholesterol oxidase from Streptomyces has been used in a study to assess the relationship between the micellar structure of model bile and the activity of esterase. Cholesterol oxidase from Streptomyces has also been used in a study to investigate the effects of sphingomyelin degradation on cell cholesterol oxidizability and steady-state distribution between the cell surface and the cell interior. Cholesterol oxidase is used to determine serum cholesterol. The enzyme also finds application in the microanalysis of steroids in food samples and in distinguishing 3-ketosteroids from 3β-hydroxysteroids. Transgenic plants expressing cholesterol oxidase are being investigated in the fight against the cotton boll weevil. CHOD has also been used as a molecular probe to elucidate cellular membrane structures. Form Lyophilized powder containing bovine serum albumin and sugars as stabilizers Enzyme Commission Number EC 1.1.3.6 Activity > 20 units/mg protein CAS No 9028-76-6 Molecular Weight mol wt ~34 kDa Isoelectric point 5.1 ± 0.1 and 5.4 ± 0.1 pH Stability pH 5.0 – 10.0 (25°C, 20hr) Michaelis Constant 4.3 x 10‾5M (Cholesterol) Unit Definition One unit will convert 1.0 μmole of cholesterol to 4-cholesten-3-one per min at pH 7.5 at 25°C. Note: 4-cholesten-3-one may undergo isomerization. Optimum pH 6.5 − 7.0 Optimum temperature 45 – 50°C Thermal stability Below 45°C (pH 7.0, 15min) Storage −20°C Buffer 50 mM potassium phosphate buffer, pH 7.0: soluble (Cold) Inhibitors Ionic detergents, Hg++, Ag+ Synonyms EC 1.1.3.6, cholesterol-O2 oxidoreductase; 3β-hydroxy steroid oxidoreductase; 3β-hydroxysteroid:oxygen oxidoreductase; 9028-76-6 category Enzyme(c2117) cas_num 9028-76-6 Basic Info-
Product Name:
Cholesterol oxidase
Other Name:Cholesterol oxidase;Oxidase,cholesterol;E.C. 1.1.3.6;EC 1.1.3.6;3-Hydroxysteroid oxidase;Cholesterin oxidase;Cholesterol oxidases;Cholesterin oxidases;3-Hydroxysteroid oxidases;131598-37-3
CAS No.:9028-76-6
Molecular Weight:0.00000
EC Number:232-842-1
HScode:35079090
Categories:
Characteristics-
PSA:
0.00000
XLogP3:0.00000
Appearance:pale yellow solution (slightly hazy)
Water Solubility:50 mM potassium phosphate buffer, pH 7.0: soluble (Cold)
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Respiratory sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Egypt
Cholesterol oxidase
25 Apr 16, 2024 Post an enquiry for this product