Native Proteus vulgaris Chondroitinase ABC
1 Inquiries
9024-13-9
2026-06-28
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Native Proteus vulgaris Chondroitinase ABC Cat No NATE-0131 Description Chondroitinase ABC catalyzes the eliminative degradation of polysaccharides containing (1-4)-β-D-hexosaminyl and (1-3)-β-D-glucuronosyl or (1-3)-α-L-iduronosyl linkages to disaccharides containing 4-deoxy-β-D-gluc-4-enuronosyl groups. It acts on chondroitin 4-sulfate, chondroitin 6-sulfate, and dermatan sulfate, and acts slowly on hyaluronate. The molecular weight is found to be approximately 120 kDa with 2 non-identical subunits of molecular masses 86 kDa and 32 kDa. The pH optimum is found to be 8.0 with chondroitin sulfate and 6.8 with hyaluronic acid and tempeRature optimum is 37°C. 1 mM Zn2+ acts as an inhibitor, while 0.05 M acetate is an activator of the enzyme. Abbr Chondroitinase ABC, Native (Proteus vulgaris) Alias ChS ABC lyase Source Proteus vulgaris Applications The enzyme has been used to study the consequences of inducing acute, long-lasting changes in chondroitin sulfate proteoglycans using adult rat brain cells. Glycosaminoglycans have been digested with chondroitinase ABC for chondroitin/dermatan sulfate quantitation in keratocyte cell cultures obtained from fresh bovine corneal stromae. Form lyophilized powder. Enzyme Commission Number EC 4.2.2.4 Activity 50-250 units/mg protein (using chondroitin sulfate C as substrate); 0.3-3 units/mg solid (using chondroitin sulfate C as substrate) CAS No 9024-13-9 Unit Definition One unit will liberate 1.0 μmole of 2-acetamido-2-deoxy-3-O-(β-D-gluc-4-ene-pyranosyluronic acid)-4-O-sulfo-D-galactose from chondroitin sulfate A or 1.0 μmole of 2-acetamido-2-deoxy-3-O-(β-D-gluc-4-ene-pyranosyluronic acid)-6-O-sulfo-D-galactose from chondroitin sulfate C per min at pH 8.0 at 37°C. Storage −20°C Buffer 0.01% bovine serum albumin aqueous (BSA) solution: soluble Synonyms EC 4.2.2.4, chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9 category Specialty Chemicals(c26) cas_num 9024-13-9 Basic Info-
Product Name:
Chondroitin-sulfate-ABC endolyase
Other Name:Chondroitin-sulfate-ABC endolyase;Endolyase,chondroitin ABC;Chondroitin ABC eliminase;E.C. 4.2.2.4;Chondroitinase;Chondroitinase ABC;Chondroitin ABC endolyase;Chondroitin sulfate depolymerase;Chondroitin sulfate ABC lyase;E.C. 4.2.2.20;Condoliase;SI 6603
CAS No.:9024-13-9
Molecular Weight:130.077
Exact Mass:130.017853
Categories:
Characteristics-
XLogP3:
-2.10
Density:1.7±0.1 g/cm3
Boiling Point:401.4±48.0 °C at 760 mmHg
Flash Point:196.5±29.6 °C
Refractive Index:1.596
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Canada
Chondroitinase ABC from Proteus vulgaris, Recombinant
1 Nov 10, 2023 Post an enquiry for this product