Native Escherichia coli N-Acetylneuraminic Acid Aldolase
9027-60-5
Yes
2026-11-22
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Details
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Seller Information
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Description
ProductName Native Escherichia coli N-Acetylneuraminic Acid Aldolase Cat No NATE-0490 Description In enzymology, a N-acetylneuraminate lyase (EC 4.1.3.3) is an enzyme that catalyzes the chemical reaction:N-acetylneuraminate↔ N-acetyl-D-mannosamine + pyruvate. Hence, this enzyme has one substrate, N-acetylneuraminate, and two products, N-acetyl-D-mannosamine and pyruvate. This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. This enzyme participates in aminosugars metabolism. Abbr NPL, Native (Escherichia coli) Alias NPL; NALase; NANA lyase Source Escherichia coli Applications This enzyme is useful for enzymatic determination of N-acetylneuraminic acid and sialic acid when coupled with the related enzymes in clinical analysis. For industrial use, this enzyme is useful for enzymatic synthesis of sialic acid. Used in the Sialic Acid Quantification Kit, SIALIC-Q Form Lyophilized powder containing potassium phosphate buffer salt Enzyme Commission Number EC 4.1.3.3 Activity > 20 units/mg protein (biuret) CAS No 9027-60-5 Molecular Weight mol wt ~98 kDa Isoelectric point 4.6 ± 0.1 pH Stability pH 6.0–9.0 (10°C, 25hr) Michaelis Constant 2.5 x 10‾3M (N-Acetylneuraminic acid) Structure 3 subunits (approx. 35 kDa) per mol of enzyme Unit Definition One unit will release 1.0 μmole of pyruvate from NANA per min at pH 7.7 at 37°C. Optimum pH 7.5– 8.0 Optimum temperature 70°C Thermal stability Below 65°C (pH 7.5, 30 min) Storage −20°C Inhibitors p-Chloromercuribenzoate, sodium dodecyl sulfact, Hg++, Ag+ Synonyms N-acetylneuraminic acid aldolase; acetylneuraminate lyase; sialic aldolase; sialic acid aldolase; sialate lyase; N-acetylneuraminic aldolase; neuraminic aldolase; N-acetylneuraminate aldolase; neuraminic acid aldolase; N-acetylneuraminic acid aldolase; neuraminate aldolase; N-acetylneuraminic lyase; N-acetylneuraminic acid lyase; NPL; NALase; NANA lyase; acetylneuraminate pyruvate-lyase; N-acetylneuraminate pyruvate-lyase; 9027-60-5; EC 4.1.3.3 category Enzyme(c2117) cas_num 9027-60-5 Basic Info-
Product Name:
N-Acetylneuraminate lyase
Other Name:N-Acetylneuraminate lyase;Lyase,acetylneuraminate;N-Acetylneuraminic aldolase;N-Acetylneuraminate aldolase;N-Acetylneuraminic acid aldolase;Sialic aldolase;Sialic acid aldolase;E.C. 4.1.3.3;Neuraminic aldolase;Neuraminic acid aldolase;N-Acylneuraminic aldolase;N-Acylneuraminate aldolase;N-Acylneuraminic acid aldolase;Neuraminate aldolase;N-Acylneuraminic lyase;Acetylneuraminate pyruvate-lyase;Acylneuraminate pyruvate-lyase;N-Acetylneuraminate pyruvatelyase;N-Acylneuraminate lyase;N-Acetylneuraminic acid lyase;Sialate lyase;Sialic acid lyase;Sialate pyruvate-lyase;N-Acetylneuraminic lyase;N-Acetylneuraminic lyases;N-Acetylneuraminate lyases
CAS No.:9027-60-5
Categories:
Characteristics-
Appearance:
slightly yellow powder
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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