Native Rat Thioredoxin Reductase
9074-14-0
2026-07-27
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Native Rat Thioredoxin Reductase Cat No NATE-0713 Description Thioredoxin reductase (TrxR) is an NADPH-dependent oxidoreductase containing one FAD per subunit that reduces the active site disulfide in oxidised thioredoxin (Trx). The molecular weight of the isozymes from mammalian sources vary between 55-67 kDa as compared with 35 kDa in prokaryotes, plants or yeast. The substrate specificity of the mammalian enzyme is much broader than the prokaryotic enzyme reducing both mammalian and E. coli thioredoxins as well as well as non-disulfide substrates such selenite, lipoic acids, lipid hydroperoxides and hydrogen peroxide. Abbr TR, Native (Rat) Alias TrxR Source Rat liver Species Rat Applications Thioredoxin Reductase from rat liver can be used for studying the uptake and reduction of a-lipoic acid by utilizing reducing capacity of human erythr ocytes. The product can also be used for studying the activation mechanism of transglutaminase 2 (TG2) in the extracellular matrix by using Thioredoxin. Form buffered aqueous glycerol solution; Solution in 50 mM Tris-HCl, pH 7.5, 300 mM NaCl, 1 mM EDTA, and 10% glycerol. Enzyme Commission Number EC 1.8.1.9 Activity > 100 units/mg protein (Bradford) CAS No 9074-14-0 Unit Definition One unit will cause an increase in absorbance of 1.0 at 412 nm (when measured in a non-coupled assay containing DTNB alone as substrate) per minute at pH 7.0 at 25°C. Storage −20°C Pathway Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Oxidative Stress, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem; Pyrimidine metabolism, organism-specific biosystem Function NADP binding; electron carrier activity; flavin adenine dinucleotide binding; oxidoreductase activity; protein disulfide oxidoreductase activity; thioredoxin-disulfide reductase activity Synonyms NADP-thioredoxin reductase; NADPH-thioredoxin reductase; thioredoxin reductase (NADPH); NADPH2:oxidized thioredoxin oxidoreductase; thioredoxin-disulfide reductase; EC 1.8.1.9; TrxR; 9074-14-0 category Specialty Chemicals(c26) cas_num 9074-14-0 Basic Info-
Product Name:
RYNTR
Other Name:RYNTR;EC 1.6.4.5;THIOREDOXIN REDUCTASE;THIOREDOXIN REDUCTASE RAT LIVER;THIOREDOXIN: NADP+ OXIDOREDUCTASE;THIOREDOXIN REDUCTASE, FROM E. COLI;thioredoxin reductase from rat liver;NADPH:OXIDISED THIOREDOXIN OXIDOREDUCTASE;THIOREDOXIN REDUCTASE, YEAST, RECOMBINANT;NADPH: OXIDIZED THIOREDOXIN OXIDOREDUCTASE
CAS No.:9074-14-0
Molecular Formula:C36H24Br2F3N3O4S2
Molecular Weight:843.527
Exact Mass:840.952698
Categories:
Characteristics-
XLogP3:
11.64
Density:1.6±0.1 g/cm3
Boiling Point:912.0±75.0 °C at 760 mmHg
Flash Point:505.3±37.1 °C
Refractive Index:1.686
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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