Cambinol
14513-15-6
90%
2026-07-27
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Cambinol Cat No CEI-0648 Description An inhibitor of NAD-dependent deacetylase activity of human SIRT1 (IC50 = 56 µM) and SIRT2(IC50 = 59 µM). Acts as an antitumor agent. Treatment of BCL6-expressing Burkitt lymphoma cells with Cambinol induces apoptosis accompanied by hyperacetylation of BCL6 and p53. Alias NSC-112546 Appearance Off-white solid Product Overview A SIRT1 inhibitor CAS No 14513-15-6 Molecular Weight 403.52 Purity >90% by HPLC Storage -20 centigrade Synonyms NSC-112546 Targets SIRT1 Molecular Formula C₂₁H₁₆N₂O₂S Chemical Name 5-[(2-hydroxy-5,8-dihydronaphthalen-1-yl)methyl]-6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one Solubility DMSO Shipping Conditions Gel pack category Specialty Chemicals(c26) cas_num 14513-15-6 Basic Info-
Product Name:
Tetrahydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-Pyrimidinone
Other Name:NSC-1125476;Tetrahydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-Pyrimidinone;SIRT1/2 Inhibitor IV, Cambinol;SIRT1/2 Inhibitor IV;CAMBINOL;NSC-1125476;Cambinol;NSC-1125476, Tetrahydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-Pyrimidinone, 5-(2-Hydroxynaphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one, 5-[(2-hydroxy-1-naphthyl)methyl]-2-mercapto-6-phenyl-4(3H)-Pyrimidinone;5-(2-Hydroxynaphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
CAS No.:14513-15-6
Molecular Formula:C21H16N2O2S
InChIKeys:RVNSQVIUFZVNAU-UHFFFAOYSA-N
Molecular Weight:360.43
Exact Mass:360.09324893
UNII:8S2PHY4FNC
NSC Number:112546
DSSTox ID:DTXSID40390573
Categories:
Characteristics-
PSA:
100.97000
XLogP3:4.54910
Density:1.41g/cm3
Melting Point:235 °C(dec.)
Boiling Point:667ºC
Flash Point:357.2ºC
Refractive Index:1.771
Water Solubility:<0.1mg/mL
Storage Conditions:Room temp
Vapor Pressure:2.12E-18mmHg at 25°C
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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