Vinblastine Sulfate
143-67-9
98%
2026-08-11
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Vinblastine Sulfate Cat No CEI-0563 Description A plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Inhibits normal microtubule assembly and causes aberrant tubulin polymerization. Blocks binding of tubulin to microtubule proteins. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent. Alias Vincaleukoblastine sulfate salt; VLB Appearance White solid Product Overview A tubulin polymerrization inhibitor CAS No 143-67-9 Molecular Weight 271.27 Purity >98% by HPLC Storage RT Synonyms Vincaleukoblastine sulfate salt; VLB Targets MGMT Molecular Formula C₄₆H₅₈N₄O₉S.H₂SO₄ Solubility DMSO (100 mM) Shipping Conditions RT category Antineoplastic Agents(c1417) cas_num 143-67-9 Basic Info-
Product Name:
Vinblastine sulfate
Other Name:Vincaleukoblastine,sulfate (1:1) (salt);2H-3,7-Methanoazacycloundecino[5,4-b]indole,vincaleukoblastine deriv.;1H-Indolizino[8,1-cd]carbazole,vincaleukoblastine deriv.;29060LE;NSC 49842;Velban;Velbe;Vinblastine sulfate;Vincaleucoblastine sulfate;Vincaleukoblastine sulfate;Exal;VLB monosulfate;Velsar;Alkaban-AQ
CAS No.:143-67-9
Molecular Formula:C46H58N4O9.H2O4S
InChIKeys:InChIKey=KDQAABAKXDWYSZ-PNYVAJAMSA-N
Molecular Weight:909.05
Exact Mass:908.387756
EC Number:205-606-0
NSC Number:49842
UN Number:2811
DSSTox ID:DTXSID7047853
HScode:2942000000
Categories:
Characteristics-
PSA:
237.08000
XLogP3:4.35970
Appearance:white powder
Density:1.37 g/cm3
Melting Point:284-285 °C
Water Solubility:H2O: 10 mg/mL
Storage Conditions:2-8°C
Specific rotation:-21.7 º (c=2, CH3OH 21 ºC)
Air and Water Reactions:Water soluble..Rapidly hydrolyzes.
Reactive Group:Alcohols and Polyols
Reactivity Profile:This compound is sensitive to light, hydrolysis, oxidation, and heat. It is very hygroscopic. (NTP, 1992).
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Serious eye damage, Category 1
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product