BML-277
516480-79-8
98%
2026-08-03
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName BML-277 Cat No CEI-0960 Description A highly selective inhibitor of Chk2 (IC50=15 nM). Displays <25% inhibition of 35 other kinases at 10 uM). It possesses potent radioprotective activity and prevents apoptosis of human T-cells subjected to ionizing radiation (EC50= 3-7.6 μM). It is a useful tool for determining the role of Chk2 in cellular signaling. Abbr BML-277(CHEK2) Alias 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide, Chk2 Inhibitor II Appearance Off white solid Product Overview CHK2 inhibitor CAS No 516480-79-8 Molecular Weight 363.8 Purity >98% (TLC; 1:1 ethylacetate: hexane; Rf=0.17); NMR (Conforms) Synonyms 2-(4-(4-chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide, Chk2 Inhibitor II Targets CHK2 Molecular Formula C20H14ClN3O2 Solubility May be dissolved in DMSO (20 mg/ml); or Ethanol (20 mg/ml) category Specialty Chemicals(c26) cas_num 516480-79-8 Basic Info-
Product Name:
CHK2 INHIBITOR II
Other Name:BML-277;2-[4-(4-Chlorophenoxy)phenyl]-1H-benzimidazole-5-carboxylic acid amide;C 3742;C 3742 BML-277;2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide hydrate;Chk2 Inhibitor II hydrate;InSolution? Chk2 Inhibitor II;2-[4-(4-chlorophenoxy)phenyl]-1H-benzimidazole-6-carboxamide
CAS No.:516480-79-8
Molecular Formula:C20H14ClN3O2
InChIKeys:UXGJAOIJSROTTN-UHFFFAOYSA-N
Molecular Weight:363.803
Exact Mass:363.077
NSC Number:741899
DSSTox ID:DTXSID40433479
Categories:
Characteristics-
PSA:
81
XLogP3:4.3
Appearance:tan solid
Density:1.390±0.06 g/cm3(Predicted)
Boiling Point:637.097°C at 760 mmHg
Flash Point:339.104ºC
Refractive Index:1.703
Water Solubility:DMSO: 18 mg/mL
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product