L-NAME hydrochloride
51298-62-5
99%
2026-07-14
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Product Description
-
Seller Information
-
Description
ProductName L-NAME hydrochloride Cat No CEI-0592 Description A pro-drug of L- NG-Nitro-L-arginine (L-NOARG). Hydrolysis of the methyl ester of L-NAME by cellular esterases converts it into a fully functional L-NOARG that exhibits some selectivity for inhibition of neuronal and endothelial NOS isoforms (Ki values of 15 nM, 39 nM, and 4.4 µM for nNOS (bovine), eNOS (human), and iNOS (mouse), respectively). L-NAME inhibits cGMP formation in endothelial cells with an IC50 of 3.1 µM (in the presence of 30 µM arginine) and reverses the vasodilation effects of acetylcholine in rat aorta rings with an EC₅₀ of 0.54 µM. Alias NG-Nitro-L-arginine methyl ester hydrochloride Appearance White to off-white solid Product Overview A pro-drug of the NOS inhibitor L- NG-Nitro-L-arginine CAS No 51298-62-5 Molecular Weight 278.35 Purity >99% by TLC Storage -20 centigrade Synonyms NG-Nitro-L-arginine methyl ester hydrochloride Targets NOS1, NOS3, Nos2 Molecular Formula C 7 H 15 N 5 O 4 . HCl Solubility DMSO (~200 mg/ml) or Ethanol (~40 mg/ml) Shipping Conditions Gel pack Amino Acid Sequence H-Arg(NO2)-OMeHCl category Amino Acids and Derivatives(c1517) cas_num 51298-62-5 Basic Info-
Product Name:
L-Ornithine, N5-[imino(nitroamino)methyl]-, methyl ester, hydrochloride (1:1)
Other Name:L-Ornithine,N5-[imino(nitroamino)methyl]-,methyl ester,hydrochloride (1:1);L-Ornithine,N5-[imino(nitroamino)methyl]-,methyl ester,monohydrochloride;Nitroarginine methyl ester hydrochloride;NG-Nitroarginine methyl ester hydrochloride;L-NAME hydrochloride;117175-74-3;62680-89-1;158321-17-6;952656-08-5
CAS No.:51298-62-5
Molecular Formula:C7H15N5O4.ClH
InChIKeys:InChIKey=QBNXAGZYLSRPJK-JEDNCBNOSA-N
Molecular Weight:269.69
Exact Mass:269.089081
EC Number:257-116-1
UNII:TFX6A1PRZ1
DSSTox ID:DTXSID10199292
HScode:29299090
Categories:
Characteristics-
PSA:
149
Appearance:white to off-white powder
Melting Point:157-161 °C (dec.)
Boiling Point:383.5°C at 760 mmHg
Flash Point:185.8ºC
Refractive Index:15 ° (C=3, MeOH)
Water Solubility:H2O: 50 mg/mL
Storage Conditions:2-8°C
Specific rotation:14.5 º (c=3, CH3OH)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Location:
Shirley, New York 11967, USA
-
Payment Terms:
TT against copy of documents,D/P
-
Average lead Time:
15
-
Total Annual Revenue:
$1 million-$2.5 million
-
Year of Establishment:
2004
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product