Okadaic acid
78111-17-8
97%
2026-08-08
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Okadaic acid Cat No CEI-0611 Description A Potent inhibitor of protein phosphatases 1 and 2A in numerous cell types. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Non-phorbol type tumor promoter. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells, but inhibits glucocorticoid-induced apoptosis in T-cell hybridomas. Alias OA Appearance White solid Product Overview A protein phosphatsae inhibitor CAS No 78111-17-8 Molecular Weight 283.92 Purity >97% by TLC Storage -20 centigrade Synonyms OA Targets phosphatase Molecular Formula C₄₄H₆₈O₁₃ Solubility DMSO (25 mg/ml) Shipping Conditions Gel pack category Specialty Chemicals(c26) cas_num 78111-17-8 Basic Info-
Product Name:
Okadaic acid
Other Name:1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid,α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-,(αR,2S,5R,6R,8S)-;Acanthifolicin,9,10-deepithio-9,10-didehydro-;1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid,α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-,(αR,2S,5R,6R,8S)-;Spiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran],acanthifolicin deriv.;1,7-Dioxaspiro[5.5]undecane,acanthifolicin deriv.;(αR,2S,5R,6R,8S)-α,5-Dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-1,7-dioxaspiro[5.5]undec-10-ene-2-propanoic acid;Okadaic acid;77238-08-5
CAS No.:78111-17-8
Molecular Formula:C44H68O13
InChIKeys:InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N
Molecular Weight:805
Exact Mass:805.00
EC Number:616-589-8
Color/Form:Crystals from dichloromethane/hexane; crystals from benzene-CHCl3|White crystals or powder
Categories:
Characteristics-
PSA:
182.83000
XLogP3:5.21360
Appearance:white crystals or powder
Density:1.0795
Melting Point:164-166 °C
Boiling Point:672.95°C (rough estimate)
Flash Point:269.4ºC
Refractive Index:1.5940 (estimate)
Water Solubility:It is soluble in ethanol (25 mg/ml), DMSO (25 mg/ml), methanol (<1 mg/ml), chloroform, acetone, ethyl acetate, DMF, and dimethylsulfoxide. Insoluble in water, unless first dissolved in organic solvents, such as DMSO or ethanol.
Storage Conditions:-20ºC
Toxicity:LD50 i.p. in mice: 192 mg/kg (Shibata)
PKA:3.87±0.16
Experimental Properties:Ionophoric polyether identified in marine organisms
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product