Actinomycin D
50-76-0
99%
2026-07-15
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Product Description
-
Seller Information
-
Description
ProductName Actinomycin D Cat No CEI-1044 Description Transcription inhibitor Abbr Actinomycin D(Transcription) Source Synthetic Appearance White Solid CAS No 50-76-0 Molecular Weight 1255.43 Purity >99% Storage -20 centigrade Targets Transcription Molecular Formula C62H86N12O16 Solubility Soluble to 50mM in DMSO. Shipping Conditions Blue Ice or 4 centigrade category Antineoplastic Agents(c1417) cas_num 50-76-0 Basic Info-
Product Name:
actinomycin D
Other Name:ad;actd;acto-d;nsc3053;AD(VAN);cosmegen;Cosmogen;nci-c04682;nci-co4682;oncostatink
CAS No.:50-76-0
Molecular Formula:C62 H86 N12 O16
InChIKeys:RJURFGZVJUQBHK-UHFFFAOYSA-N
Molecular Weight:1255.44
Exact Mass:1254.628418
EC Number:232-485-1
NSC Number:191297|684906
UN Number:2811
DSSTox ID:DTXSID9020031
Color/Form:Bright red crystalline powder|Yellow lyophilized powder. /Cosmegen/
HScode:29419000
Categories:
Characteristics-
PSA:
359.98000
XLogP3:-4.03
Appearance:red, powder powder
Density:1.4±0.1 g/cm3
Melting Point:251-253 °C
Boiling Point:1386.0±65.0 °C at 760 mmHg
Flash Point:87℃
Refractive Index:1.656
Water Solubility:H2O: soluble ;ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble
Storage Conditions:2-8°C
Vapor Pressure:0 mm Hg at 25 °C (est)
Toxicity:Oral-rat LD50:7.2 mg/kg; Oral-Mouse LD50: 13 mg/kg
Flammability characteristics:Flammable; burning releases toxic nitrogen oxide fumes; drug side effects: dermatitis, bone marrow damage, digestive system affected
Dissociation Constants:pKa = 11.90
Experimental Properties:Bright red, rhomboid prisms from abs alcohol; decomposes at 241.5-243 °C; specific optical rotation: -315 deg at 28 °C/D (c = 0.25 in methanol); absorption max (methanol): 244, 441 nm; dilute solutions are very sensitive to light; soluble in alcohol, propylene glycol, water and glycol mixtures. /Trihydrate/|It is light sensitive and should be protected from heat and moisture.|Hydroxyl radical reaction rate constant = 2.8X10-10 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions:Water soluble.
Reactive Group:Amides and Imides
Reactivity Profile:ACTINOMYCIN D can react with strong oxidizing agents, strong acids and strong bases. (NTP, 1992)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 1, Oral
Carcinogenicity, Category 1A
Reproductive toxicity, Category 1A
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H300 Fatal if swallowed
H350 May cause cancer
H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Location:
Shirley, New York 11967, USA
-
Payment Terms:
TT against copy of documents,D/P
-
Average lead Time:
15
-
Total Annual Revenue:
$1 million-$2.5 million
-
Year of Establishment:
2004
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product