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Orlistat 99% White crystalline powder Human API Arshine

Name: Orlistat 99% White crystalline powder Human API Arshine
Brand: Arshine
Price: 580 USD
Availability: InStock

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CAS No.:

96829-58-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai/qingdao/ningbo/guangzhou

Brand:

Arshine

Packaging:

1KG

Price valid (until):

2022-12-31

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Arshine Group Co., Ltd.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

cosmetic additives,Veterinary APIs,Feed additives,medical and pharmaceutical packaging materials,pharmaceutical equipment,Natural Nutrition Ingredients

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Product Description
Seller Information
Inquiry History

Description

Orlistat is an obesity treatment drug that does not act on the central nervous system. It only acts on the gastrointestinal tract. By inhibiting the lipase in the gastrointestinal tract, it prevents the hydrolysis of triacylglycerol into free fatty acids and monoacylglycerides, reduces the absorption of fat (triacylglycerol) in the intestinal mucosa, and promotes the excretion of fat from the body. . Lipase is an enzyme necessary for the decomposition of fat in the gastrointestinal tract. This product can be combined with the serine residue of gastric and pancreatic lipase to inactivate the lipase, so that it cannot decompose the fat in food into free fatty acids, and inhibit the formation of fat. Utilization and absorption, in addition, this product can still reduce the risk factors related to obesity.

Item	Results	Specifications
Identification HPLC IR	HPLC retention time Conforms with the reference Conforms	HPLC retention time Conforms with the reference Conforms
Specific Optical Rotation	-49.2°	-48.0° to -51.0°
Water content	0.1%	NMT 0.2%
Related substances I a. Orlistat related compound A	Not detected	NMT 0.2%
Related substances II a. Orlistat related compound B	0.01%	NMT 0.05%
Related substances III a. Formylleucine b. Orlistat related compound C c. Orlistat open ring epimer d. D- Leucine orlistat e. Individual unidentified impurity	Not detected Not detected 0.03% 0.04% 0.06%	NMT 0.2% NMT 0.05% NMT 0.2% NMT 0.2% NMT 0.1%
Related substances IV a. Orlistat related compound D b. Orlistat open ring amide	0.14% 0.03%	NMT 0.2% NMT 0.1%
Related substances V a. Orlistat related compound E	0.06%	NMT 0.2%
Total impurities(I to V)	0.8%	NMT 1.0%
Residual solvents	Methanol: 0.1% EtOAc: Not detected n- Heptane: Less than 0. 1%	Methanol: NMT 0.3% EtOAc: NMT 0.5% n- Heptane: NMT 0.5%
Residue on ignition	Less than 0. 1%	NMT 0. 1%
Heavy Metals as Pb	Less than 20ppm	NMT 20ppm
Assay by HPLC (Orlistat)	99.2%	NLT 98.0% to 101 .5% (on anhydrous,solvent-free basis)
Conclusion:	The results conform with the USP-43 specification

Certificates

Basic Info

Product Name:

Tetrahydrolipstatin

Other Name:

L-Leucine,N-formyl-,(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester;L-Leucine,N-formyl-,1-[(3-hexyl-4-oxo-2-oxetanyl)methyl]dodecyl ester,[2S-[2α(R*),3β]]-;Tetrahydrolipstatin;(-)-Tetrahydrolipstatin;Ro 18-0647/002;Orlistat;Xenical;Listata;Alli;111397-16-1;1236363-36-2

CAS No.:

96829-58-2

Molecular Formula:

C29H53NO5

InChIKeys:

InChIKey=AHLBNYSZXLDEJQ-FWEHEUNISA-N

Molecular Weight:

495.73500

Exact Mass:

495.73

UNII:

95M8R751W8

DSSTox ID:

DTXSID8023395

NCI Thesaurus Code:

C29303

Color/Form:

Crystals

ATC Code:

A08AB01|A - Alimentary tract and metabolism

HScode:

29322090

Categories:

Drug Metabolism

Characteristics

PSA:

81.70000

XLogP3:

Appearance:

Solid

Density:

0.976 g/cm3

Melting Point:

39-41 °C

Boiling Point:

615.9ºC at 760 mmHg

Flash Point:

326.3ºC

Refractive Index:

1.469

Water Solubility:

Practically insoluble in water

Storage Conditions:

2-8ºC

Vapor Pressure:

9.77X10-14 mm Hg at 25 deg C (est)

Specific rotation:

Specific optical rotation at 20 °C: -32.0 deg ( c = 1 in chloroform)

Henrys Law Constant:

Henry's Law constant = 1.13X10-9 atm-cu m/mole at 25 °C (est)

Dissociation Constants:

Orlistat has no pKa within the physiological range

Collision Cross Section:

241.2 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

Hydroxyl radical reaction rate constant = 4.52x10-13 cu cm/molec-sec at 25 °C (est)

See More Tetrahydrolipstatin Properties 

Hazard Identification

Classification of the substance or mixture

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	H412 Harmful to aquatic life with long lasting effects
Prevention	P273 Avoid release to the environment.
Response	none
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tetrahydrolipstatin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
cosmetic additives,Veterinary APIs,Feed additives,medical and pharmaceutical packaging materials,pharmaceutical equipment,Natural Nutrition Ingredients

Location:
Block 14, No.100, Luyun Road,Changsha 410205,China.

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
Above $100 million

Total Employees:
201-300

Year of Establishment:
2012

Certifications:
FAMI-QS,AEO,ISO9001

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Arshine Group Co., Ltd. (Arshine Group for short) was founded in Shenzhen in 2007. Over the decades, Arshine has maintained sound development and rapid global expansion with an average annual growth rate of over 30%. Based on China and looking at the world, the Group has become a first-class and industry-leading professional health industry chain service group in China, with an annual turnover of over $150million.
Arshine Group supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates, pharmaceutical equipment, medical and pharmaceutical packaging materials, medical devices, etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Arshine's marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.
Arshine Group has been highly recognized by all sectors of society since its establishment! Arshine is an AA Grade customer of Sinosure in Hunan Province and an AEO-accredited enterprise of China Customs. It has been certified by ISO9001 and EU FAMI-QS, and has obtained Class III Medical Device Trading Permit. As a member of the Board of Directors of the China Chamber of Commerce for Import & Export of Medicines & Health Products, Arshine has been awarded the title of "Quality Supplier and Partner in the International Market" by the Chamber in recent years. As the best human resource management company in Hunan Province, the Group has been awarded as Employer of the Year for several successive years.
In the future, Arshine Group will expand its business in the health industry, increase investment in R&D and production, and gradually become a trading, service and investment integrated group enterprise with trading business as its core. Arshinees will stay true to the mission of serving the global health industry and helping create a win-win situation.

Inquiry History

6 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Arab Emirates	orlistat	1000 KG	Feb 25, 2025
Malaysia	Orlistat 99% powder C29H53NO5 factory price safety delivery likes	1 KG	Oct 19, 2023
Netherlands	Factory hot sale Orlistat Pure Raw Steroid Powder	100 G	Apr 11, 2025
United States	Orlistat	1 KG	Oct 1, 2024
Turkey	ORLISTAT	25 KG	Apr 2, 2024
Switzerland	orlistat 99% White powder orlistat	20000 MT	Sep 5, 2023

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