15183-37-6
1 Inquiries
15183-37-6
kg
2023-02-05
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceEstetrol is a 3-hydroxy steroid that is 17beta-estradiol which has been substituted at the 15alpha and 16alpha positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver. It has a role as an estrogen, an estrogen receptor agonist, a human metabolite, a human xenobiotic metabolite and an oral contraceptive. It is a 3-hydroxy steroid, a 17beta-hydroxy steroid, a 16alpha-hydroxy steroid, a 15alpha-hydroxy steroid and a steroid hormone. It derives from a hydride of an estrane.|Estetrol has been investigated for the treatment and basic science of Prostatic Neoplasms.|Estetrol anhydrous is an Estrogen. The mechanism of action of estetrol anhydrous is as an Estrogen Receptor Agonist.|Therapeutic Estetrol is a synthetic steroid similar or identical to endogenous estetrol, a short-acting estrogen with both agonistic and antagonistic estrogen receptor activity. Administered orally, therapeutic estetrol binds to the estrogen receptor and as a selective estrogen receptor modulator (SERM) exhibits estrogen agonism in certain tissues and estrogen antagonism in others. Displaying weak estrogen activity in the uterus, estetrol acts as an estrogen antagonist in breast tissue. Produced solely by the human fetal liver, endogenous estetrol is the primary estrogen metabolite of estrogen biosynthesis in the human fetal liver.|A metabolite of ESTRIOL with a 15-alpha-hydroxyl group. Estetrol can be converted from estriol sulfate or DEHYDROEPIANDROSTERONE SULFATE by the fetal-placental unit.
Off-White SolidBasic Info-
Product Name:
ESTETROL
Other Name:1,3,5(10)-ESTRATRIEN-3,15-ALPHA, 16-ALPHA, 17-BETA-TETROL;15-ALPHA-HYDROXYESTRIOL;ESTETROL;(15a,16a,17)-Estra-1,3,5(10)-triene-3,15,16,17-tetrol;15a-Hydroxyestriol;3,15a,16a,17-Tetrahydroxyestra-1,3,5(10)-triene;Estra-1,3,5(10)-triene-3,15a,16a,17-tetrol;15α-Hydroxyestriol
CAS No.:15183-37-6
Molecular Formula:C18H24O4
InChIKeys:AJIPIJNNOJSSQC-VRHMYLLRNA-N
Molecular Weight:304.38
Exact Mass:304.38
UNII:ENB39R14VF
DSSTox ID:DTXSID50164888
NCI Thesaurus Code:C68928
Color/Form:white to beige
Categories:
Characteristics-
Density:
1.343±0.06 g/cm3(Predicted)
Melting Point:233-236°C
Boiling Point:491.9±45.0 °C(Predicted)
PKA:10.22±0.70(Predicted)
Critical Temperature & Pressure:-20°C Freezer
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Seller Information
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Business Type:
Manufactory
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Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2021
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
United States
Estetrol
1 MT Jun 6, 2025 Post an enquiry for this product