THIAMINE HYDROCHLORIDE 99% white powder cas70-16-6 senwayer

3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium

Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-;3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium;Thiamine ion;3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium;118230-82-3;118743-91-2;13857-22-2;90051-60-8;1210110-55-6

70-16-6

C12H17N4OS

InChIKey=JZRWCGZRTZMZEH-UHFFFAOYSA-N

265.354

265.111755

200-425-3

4ABT0J945J

DTXSID50220251

Crystals from water

A - Alimentary tract and metabolism

2936220000

Other Chemical Drugs

104.15000

1.18890

Solid

250ºC (dec.)(lit.)

500.0 mg/mL

The drug is not highly susceptible to atmospheric oxidation but should be protected from air and light. Thiamine hydrochloride tablets should be stored in tight, light-resistant containers at a temperature less than 40 degrees C, preferably between 15-30 degrees C. Thiamine hydrochloride injection should be protected from light and stored at a temperature less than 40 degrees C, preferably between 15-30 degrees C; freezing should be avoided.

1.8X10-10 mm Hg at 25 deg C (est)

SLIGHT, CHARACTERISTIC

162.4 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|160.3 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|159 Ų [M]+ [CCS Type: TW, Method: calibrated with polyalanine]|162.8 Ų [M]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|155.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|163 Ų [M*]+

Monoclinic plates in rosette-like clusters. Slight thiazole odor; bitter taste; decomposes at 248 °C. One gram dissolves in approximately 1 mL water, 18 mL glycerol, 100 mL 95% alcohol, 315 mL absolute alcohol; more soluble in methanol. Soluble in propylene glycol. Practically insoluble in ether, benzene, hexane, chloroform. pH of 1% wt/vol solution in water 3.13; pH of 0.1% wt/vol solution in water 3.58. On exposure to air of average humidity, the vitamin absorbs an amount of water corresponding to nearly one mole, forming a hydrate.|HYGROSCOPIC; NUT-LIKE ODOR /HYDROCHLORIDE/|READILY SPLIT BY SULFITE INTO ITS PYRIMIDINE & THIAZOLE CONSTITUENTS|Crystals. MP: 196-200 °C, decomposes; practically nonhygroscopic; pKa = 4.9. Solubility in water (g/100 mL): 2.7 (25 °C); approximately 30 (100 °C). pH of 2% aqueous solution 6.5 to 7.1, more stable than the hydrochloride; suitable for enrichment of flours and feeds, multivitamin preparations /Mononitrate/|SMALL WHITE CRYSTALS OR CRYSTALLINE POWDER /HYDROCHLORIDE/|Thiamine hydrochloride in the dry state is stable. Acidic solutions having a pH below 5.5 preferably from 5.0 to 3.5 are also relatively stable. Alkalies destroy it. It is precipitated from solution by several of the alkaloidal reagents such as mercuric chloride, iodine, picric acid, tannin, and Mayer's reagent. It is sensitive to both oxidizing and reducing agents. /Hydrochloride/|For more Other Experimental Properties (Complete) data for Vitamin B1 (6 total), please visit the HSDB record page.