Risdiplam -a
3 Inquiries
1825352-65-5
25
2023-03-14
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceRisdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor [nusinersen], the biggest difference being their route of administration: nusinersen requires intrathecal administration, as does the one-time gene therapy [onasemnogene abeparvovec], whereas risdiplam offers the ease of oral bioavailability. Risdiplam was approved by the FDA in August 2020 for use in patients 2 months of age or older in the treatment of spinal muscular atrophy (SMA). Set to be substantially cheaper than other available SMA therapies, risdiplam appears to provide a novel and relatively accessible treatment option for patients with SMA regardless of severity or type.
Risdiplam is a survival of motor neuron 2 (SMN2) splicing modifier.
light yellow powder to yellow powderBasic Info-
Product Name:
Risdiplam
Other Name:7-amino-2,3-dihydro-1H-inden-4-ol;Risdiplam;RO7034067;RG7916;4H-Pyrido[1,2-a]pyrimidin-4-one, 7-(4,7-diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-;2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one;Risdiplam (RG-7916, RO-7034067);2H4]-Risdiplam
CAS No.:1825352-65-5
Molecular Formula:C22H23N7O
InChIKeys:ASKZRYGFUPSJPN-UHFFFAOYSA-N
Molecular Weight:401.46
Exact Mass:401.46
EC Number:218-362-5
UNII:76RS4S2ET1
Color/Form:Light yellow to yellow
ATC Code:M09AX10|M - Musculo-skeletal system
Categories:
Characteristics-
Density:
1.50±0.1 g/cm3(Predicted)
PKA:9.41±0.20(Predicted)
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
India
Risdiplam
1 KG Feb 10, 2026 
Sweden
Risdiplam
100 G Jan 29, 2024
Sweden
Risdiplam
1 G Jan 29, 2024 Post an enquiry for this product
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