 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one for Sale > Torin 2 99% see COA Kanbei kanbei

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Torin 2 99% see COA Kanbei kanbei

Name: Torin 2 99% see COA Kanbei kanbei
Brand: kanbei
SKU: pr2304141142
Price: 1 USD
Availability: InStock

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CAS No.:

1223001-51-1

Grade:

Industrial Grade

Content:

99%

Port:

qingdao

Brand:

kanbei

Packaging:

25kg drum

Price valid (until):

2022-07-18

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Henan Lihao Chem Plant Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

90 days

Qualification:

Main Products:

PVC resin,pvc paste resin,melamine

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Product Description
Seller Information

Description

Product Description

Appearance and odor: Solid powder content/specifications: ≥98% Solubility: DMSO 20 mg/mL (46.25 mM) Water <1 mg/mL (<1 mM) ethanol <1 mg/mL (<1 mM) Use: Torin 2 is a potent selective mTOR inhibitor with IC50 of 0.25 nM in the p53−/− MEFs cell line. mTOR was 800 times more selective than PI3K and showed improved pharmacokinetic performance. ATM/ATR/DNA-PK was inhibited and EC50 was 28 nM/35 nM/118 nM in PC3 cell lines. Storage condition: -20℃

Why Choose Us

1. Well-equipped, stable and high-quality raw material supply chain, to provide customers with the best quality products.

2.Strict quality inspection process and professional certificate testing to ensure the quality level of the final product.

3.Excellent sales team can provide customers with integrated and professional services.

4. Accept various OEM & ODM services to meet the different needs of different customers，low MOQ.

5. Professional supplier and manufacturer, an integrated enterprise integrating production and sales, providing customers with one-stop service.

FAQ

FAQ
1. Do you accept customization? RE: We can provide corresponding customized solutions according to the specific needs of customers.
2. Can you provide samples? RE: We can provide samples to customers and send them to consumers in time by express.
4. How is your production capacity ?and whether it can meet customer needs in a timely manner. RE:we can produce the products required by customers in time and have sufficient production capacity.
5.How long is your lead time? RE: Within 50kg, can be shipped within 5 days. More than 50 kg, the corresponding time needs to be negotiated according to the weight of the product.
6.What is your terms of payment ? RE: Payment<=1000USD, 100% in advance. Payment>=1000USD, 50% T/T in advance ,balance before shipment. irrevocable LC at sight.
7.Do you have OEM or ODM service of product? Re: Sure. If needed, we can customize products for you.
8.How can you guarantee the goods you offer is qualified ? Re: All the goods are inspected before shipment. If the goods can't come to the quality we promise, you can ask for refund.

Product Description
R&D, intermediates.

Packing&Delivery
package:1kg small bag &25kg fiber drum

delivery:prompt delivery

Contact information
Contact name :Cindy
Wechat NO:008615503787326
whatsapp NO:+8615503787326
Email:hnkanbeichemical@163.com

Pls feel free to contact me at any time .

ECHEMI Editorial Reference

Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2.
Torin 2 is a member of the class of pyridoquinolines that is benzo[h][1,6]naphthyridin-2-one carrying additional 3-(trifluoromethyl)phenyl and 6-aminopyridin-3-yl substituents at positions 1 and 9 respectively. It is a potent inhibitor of mTOR and exhibits anti-cancer properties. It has a role as a mTOR inhibitor and an antineoplastic agent. It is an organofluorine compound, a pyridoquinoline, an aminopyridine and a primary amino compound.

Certificates

Basic Info

Product Name:

9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

Other Name:

9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one;Torin 2;9-(6-AMino-pyridin-3-yl)-...;9-(6-AMino-pyridin-3-yl)-1-(3-trifluoroMethyl-phenyl)-1H-benzo[h][1,6]naphthyridin-2-one;Torin 2, Free Base, >99%;Benzo[h]-1,6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-;9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-oneTorin 2;Torin 2 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

CAS No.:

1223001-51-1

Molecular Formula:

C24H15F3N4O

InChIKeys:

GUXXEUUYCAYESJ-UHFFFAOYSA-N

Molecular Weight:

432

Exact Mass:

432.119781

DSSTox ID:

DTXSID00679917

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

72.1

XLogP3:

4.4

Density:

1.4±0.1 g/cm3

Boiling Point:

623.66ºC at 760 mmHg

Flash Point:

331.0±31.5 °C

Refractive Index:

1.676

See More 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
PVC resin,pvc paste resin,melamine

Location:
Room 405, Unit 2, Building 1, Taiji Mansion, No. 38, Nanyang Road, Jinshui District, Zhengzhou City, Henan Province

Payment Terms:
TT against copy of documents,L/C

Average lead Time:
90 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2022
Country Product Purchase Quantity Date Posted

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More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Torin 2	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry
Torin 2	/		Creative Enzymes	Inquiry

Torin 2 99% see COA Kanbei kanbei

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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