Calcipotriol monohydrate 99% see COA Kanbei kanbei
GMP ISO 1 Inquiries
147657-22-5
Industrial Grade
99%
qingdao
kanbei
25kg drum
2022-07-18
PVC resin,pvc paste resin,melamine
-
Product Details
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceCalcipotriol monohydrate is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D3). Binding of calcipotriol (hydrate) to the VDR increases AP-1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response. Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-cell differentiation in keratinocytes.
White or almost white, crystalline powder.
ChEBI: Calcipotriol hydrate is a hydrate that is the monohydrate form of calcipotriol. It is used in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients. It has a role as an antipsoriatic. It contains a calcipotriol.CertificatesBasic Info-
Product Name:
Calcipotriol Monohydrate
Other Name:CALCIPOTRIOL MONOHYDRATE;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-Cyclohexanediol hydrate;(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β,24-triol;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-Cyclohexanediol monohydrate;1,3-Cyclohexanediol,5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-,hydrate (1:1), (1R,3S,5Z)-;Calcipotriol (Calcipotriene) Monohydrate;Calcipotriol monohydrate CRS;(1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol hydrate
CAS No.:147657-22-5
Molecular Formula:C27H42O4
InChIKeys:XBKHACNRWFKJNC-IZXATKCONA-N
Molecular Weight:430.63
Exact Mass:430.30800
EC Number:689-035-6
Color/Form:White to off-white
Categories:
Characteristics-
PSA:
61.7
XLogP3:5.02630
Water Solubility:Practically insoluble in water, freely soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
Critical Temperature & Pressure:4°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 1, Dermal
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H310 Fatal in contact with skin
Precautionary statement(s) Prevention P262 Do not get in eyes, on skin, or on clothing.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
PVC resin,pvc paste resin,melamine
-
Location:
Room 405, Unit 2, Building 1, Taiji Mansion, No. 38, Nanyang Road, Jinshui District, Zhengzhou City, Henan Province
-
Payment Terms:
TT against copy of documents,L/C
-
Average lead Time:
90 days
-
Total Annual Revenue:
$5 million-$10 million
-
Total Employees:
11-50
-
Year of Establishment:
2022
-
-
Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Egypt
calcipotriene hydrate
17 G Dec 4, 2023 Post an enquiry for this product
More from this Seller
-
-
![B-benzo[b]naphtha[2,3-d]furan-2-yl-boronic acid 99% white powder kanbei]( "B-benzo[b]naphtha[2,3-d]furan-2-yl-boronic acid 99% white powder kanbei")
-
B-benzo[b]naphtha[2,3-d]furan-2-yl-boronic acid 99% white powder kanbei
Industrial Grade / 99%
-
-
-
![high quality 8Z-Dodecenyl acetate 99% transparent liquid KANBEI]( "high quality 8Z-Dodecenyl acetate 99% transparent liquid KANBEI")
-
high quality 8Z-Dodecenyl acetate 99% transparent liquid KANBEI
Industrial Grade / 99%
-
-
-
![Sodium dihydngen phoshate anhydrous 99% see COA kanbei]( "Sodium dihydngen phoshate anhydrous 99% see COA kanbei")
-
Sodium dihydngen phoshate anhydrous 99% see COA kanbei
Industrial Grade / 99%
-
-
-
![high purity hot sale Fluralaner 99% high quality see COA KANBEI]( "high purity hot sale Fluralaner 99% high quality see COA KANBEI")
-
high purity hot sale Fluralaner 99% high quality see COA KANBEI
Industrial Grade / 99%
-
-
-
![Barium Chloride 99% see COA kanbei]( "Barium Chloride 99% see COA kanbei")
-
Barium Chloride 99% see COA kanbei
Industrial Grade / 99%
-
![B-benzo[b]naphtha[2,3-d]furan-2-yl-boronic acid 99% white powder kanbei](https://file.echemi.com/fileManage/upload/goodpicture/20230703/m20230703174142805.jpg "B-benzo[b]naphtha[2,3-d]furan-2-yl-boronic acid 99% white powder kanbei")
![high quality Benzene,1-fluoro-4-[(trans,trans)-4-pentyl[1,1-bicyclohexyl]-4-yl]- 99% transparent liquid KANBEI](https://file.echemi.com/fileManage/upload/goodpicture/20221123/m20221123165033252.jpg "high quality Benzene,1-fluoro-4-[(trans,trans)-4-pentyl[1,1-bicyclohexyl]-4-yl]- 99% transparent liquid KANBEI")
