MONOCROTALINE 99% white powder kanbei
GMP ISO
315-22-0
Industrial Grade
99%
qingdao
kanbei
25kg drum
2022-07-18
PVC resin,pvc paste resin,melamine
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceMonocrotaline is an pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant to induce pulmonary hypertension in rodents.
Monocrotaline is a pyrrolizidine alkaloid.|A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.CertificatesBasic Info-
Product Name:
Monocrotaline
Other Name:2H-[1,6]Dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione,4,5,8,10,12,13,13a,13b-octahydro-4,5-dihydroxy-3,4,5-trimethyl-,(3R,4R,5R,13aR,13bR)-;20-Norcrotalanan-11,15-dione,14,19-dihydro-12,13-dihydroxy-,(13α,14α)-;Monocrotaline;2H-[1,6]Dioxacycloundecino[2,3,4-gh]pyrrolizine,20-norcrotalanan-11,15-dione deriv.;(3R,4R,5R,13aR,13bR)-4,5,8,10,12,13,13a,13b-Octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione;Monocrotalin;(-)-Monocrotaline;2H-[1,6]Dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione,4,5,8,10,12,13,13a,13b-octahydro-4,5-dihydroxy-3,4,5-trimethyl-,[3R-(3R*,4R*,5R*,13aR*,13bR*)]-;NSC 28693;30331-79-4;48197-27-9
CAS No.:315-22-0
Molecular Formula:C16H23NO6
InChIKeys:InChIKey=QVCMHGGNRFRMAD-XFGHUUIASA-N
Molecular Weight:325.36
Exact Mass:325.36
EC Number:2017-001-1
UNII:73077K8HYV
DSSTox ID:DTXSID9020902
Color/Form:Prisms from absolute alcohol|Colorless
HScode:29399990
Categories:
Characteristics-
PSA:
96.3
XLogP3:-0.7
Appearance:white to light tan powder
Density:1.35 g/cm3
Melting Point:197-198 °C (decomp)
Boiling Point:537.3ºC at 760mmHg
Flash Point:278.7±30.1 °C
Refractive Index:1.586
Water Solubility:In water, 3.7X10+5 mg/L @ 25 deg C /Estimated/
Storage Conditions:2-8°C
Vapor Pressure:7.5X10-13 mm Hg @ 25 deg C /Estimated/
Toxicity:LD50 orally in rats: 71 mg/kg (Newberne)
Specific rotation:-54.8o (C=5 IN CHLOROFORM)
Taste:Bitter
Henrys Law Constant:Henry's Law constant = 1.3X10-12 atm-cu m/mol @ 25 °C /Estimated/
Dissociation Constants:pKa = 5.83 /Estimated/
Collision Cross Section:172.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Stereoisomer of 4,5,8,10,12,13,13a,13b-octahydro-4,5-dihydroxy-3,4,5-trimethyl- 2H-(1,6)dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione|Readily hydrolyzed with alkali; reacts readily with oxidizing agents (slowly with atmospheric oxygen) to form dihydropyrrolizine and other derivatives|Hydroxyl radical reaction rate constant = 1.2X10-10 cu cm/molec-sec @ 25 °C /Estimated/
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Carcinogenicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H351 Suspected of causing cancer
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
PVC resin,pvc paste resin,melamine
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Location:
Room 405, Unit 2, Building 1, Taiji Mansion, No. 38, Nanyang Road, Jinshui District, Zhengzhou City, Henan Province
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
90 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2022
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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