Hop Flower Extract
4 Inquiries
6754-58-1
AAAAA
98%
changsha
STAHERB
1kg/2.6kg Carton (Required by Whyte Chemicals Sarl)
Yes
2023-09-18
plant extract,Fruit powder,herb extract,Carnosic acid,Chamomile P.E.,1-Deoxynojirimycin
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceXanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities.
Solid
Xanthohumol is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells. It has a role as a metabolite, an apoptosis inducer, an antineoplastic agent, an antiviral agent, an EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor and an anti-HIV-1 agent. It is a member of chalcones, a polyphenol and an aromatic ether. It is a conjugate acid of a xanthohumol(1-).|Xanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).|Xanthohumol is a prenylated flavonoid derived from the female flowers of the hops plant (Humulus lupulus L), with potential chemopreventive and antineoplastic activities. Upon administration, xanthohumol scavenges reactive oxygen species (ROS), thereby preventing DNA damage due to oxidative stress. In addition, xanthohumol is able to increase the expression of phase II cytoprotective enzymes, thereby inactivating carcinogens. This agent exerts anti-inflammatory activity, through the inhibition of inflammation-inducing enzymes, inhibits DNA synthesis, and induces apoptosis of susceptible cancer cells. Xanthohumol also decreases the expression of C-X-C chemokine receptor 4 (CXCR4), thereby preventing cancer cell invasion.Basic Info-
Product Name:
Xanthohumol
Other Name:2-Propen-1-one,1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-,(2E)-;Xanthohumol;2-Propen-1-one,1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-,(E)-;2-Propen-1-one,1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-,(2E)-;(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one;Xantho-Flav;Xantho Flav-Pure;Xanthopure
CAS No.:6754-58-1
Molecular Formula:C21H22O5
InChIKeys:InChIKey=ORXQGKIUCDPEAJ-YRNVUSSQSA-N
Molecular Weight:354.4
Exact Mass:354.40
UNII:T4467YT1NT
NCI Thesaurus Code:C121950
HScode:29145090
Categories:
Characteristics-
PSA:
87
XLogP3:5.1
Appearance:Solid
Density:1.2±0.1 g/cm3
Melting Point:172 °C
Boiling Point:576.5ºC at 760 mmHg
Flash Point:203.4±23.6 °C
Refractive Index:1.641
Water Solubility:ethanol: soluble10mg/mL
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H317 May cause an allergic skin reaction
H400 Very toxic to aquatic life
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P391 Collect spillage.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
plant extract,Fruit powder,herb extract,Carnosic acid,Chamomile P.E.,1-Deoxynojirimycin
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Location:
No.186,Lugu Valley Garden Road, High-tech Development Zone, Changsha , Hunan, P.R. China
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
120 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2010
Changsha Staherb Natural Ingredients Co., Ltd., a good supplier of professional herb extracts, especially those with high purity and standardized production process. Our company devotes to supply high quality products and services to customers in R&D and production fields of health products, cosmetics, feed additives and biopesticides.
With cordial and professional R&D, sales and after-sales service groups, Staherb has potent capabilities both in R&D and production. The company persists in high investment on R&D of active ingredients of plants and promotes innovation on demands of customers. Upon constant R&D and tracing of new technologies and new products, Staherb makes effective cooperation with famous research institutes, such as CAS Kunming Institute of Botany, State Key Lab of Hunan Forest Products and Chemical Engineering, Hunan Agricultural University and so on.
Now the main products of Staherb are standardized high purity plant extracts, including Epimedium (10-98%), Euccomia Bark Extract (5-95%), Amygdalin (50-98%), Ursolic acid (25-98%) and Corosolic acid (1-98%). In order to meet customers’ research needs, our company also provides over 600 plant extracts, most of which are high-purity monomer plant compounds and reference substance. And some products can be supplied with milligram-scale, kilogram-scale or even to ton-scale. In addition, based upon the powerful R&D capability, Staherb can provide both products customization services and R&D outsourcing services according to customers’ specific requirements, so that to meet their continual innovation needs in the fields of natural products’ discovery and production.
Staherb endeavors to accelerate the response rate of supply chain as well as improve the service superiority upon customers’ continual innovation needs. It also devotions to establish good partnerships with customers and to construct a safe development model which is forward-looking, reciprocal and coexisting, thus to create long-term value for customers through division and cooperation as well as complementation. -
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Inquiry History4 Inquiries
Country Product Purchase Quantity Date Posted
Poland
xanthohumol
30 G Dec 8, 2023
South Korea
Xanthohumol
1 KG Jun 3, 2024
Slovakia
xanthohumol
250 G Jul 22, 2025
France
xanthohumol
10 G Feb 1, 2024 Post an enquiry for this product
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