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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 4-[(1-Pyrrolidinylsulfonyl)methyl]benzenamine for Sale > 1-[[(4-Aminophenyl)methyl]sulfonyl]-pyrrolidine CAS 334981-10-1
1-[[(4-Aminophenyl)methyl]sulfonyl]-pyrrolidine CAS 334981-10-1 buy - large image1
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1-[[(4-Aminophenyl)methyl]sulfonyl]-pyrrolidine CAS 334981-10-1

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CAS No.:

334981-10-1

Grade:

Chemical Grade

Content:

99%

Port:

Shanghai

Brand:

Entrepreneur

Packaging:

50kg/bag or as per your particular request.

Price valid (until):

2023-12-31

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Flavor & Fragrance Ingredients,Plasticizer,API,Pharmaceutical Intermediates,Thermal Powder,Plant Extract

  • Product Description

  • Seller Information

  • Description


      Description  


    1-[[(4-Aminophenyl)methyl]sulfonyl]-pyrrolidine, also known as 4-[(1-Pyrrolidinylsulfonyl)methyl]benzenamine or 4-((Pyrrolidin-1-ylsulfonyl)methyl)aniline, is a chemical compound with the CAS number 334981-10-11. It has the molecular formula C11H16N2O2S and the molecular weight 240.32 g/mol2. It is a off-white to pale yellow solid with a melting point of 170-176 °C. It belongs to the class of sulfonamides, which are organic compounds that contain a sulfonyl group attached to an amine group. It is an intermediate in the preparation of AlmotriptanIt. 


      Features  


    ❶ It is a off-white to pale yellow solid with a melting point of 170-176 °C.

    ❷ It has the molecular formula C11H16N2O2S and the molecular weight 240.32 g/mol2.

    ❸ It belongs to the class of sulfonamides, which are organic compounds that contain a sulfonyl group attached to an amine group.

    ❹ It exhibits low toxicity by oral, dermal, and inhalation routes, and can cause skin irritation, eye irritation, and respiratory irritation.


      Applications  


    1.
    1-[[(4-Aminophenyl)methyl]sulfonyl]-pyrrolidine is an intermediate in the preparation of AlmotriptanIt. 

    2.
    1-[[(4-Aminophenyl)methyl]sulfonyl]-pyrrolidine can be used as an intermediate for the synthesis of various pharmaceuticals and agrochemicals, such as inhibitors of histone deacetylase (HDAC). Such as Romidepsin, Belinostat and Panobinostat.


    Specifications  


    Product Name1-[[(4-Aminophenyl)methyl]sulfonyl]-pyrrolidine
    Cas No.334981-10-1
    Molecular FormulaC7H4Cl2N2
    Molecular Weight 240.32
    Appearance Off-white to pale yellow solid
    Density1.31
    Purity99% Min
    SolubilityChloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
    Boiling point434.2 °C at 760 mmHg
    Melting point170-176 °C
    Flash point216.4±29.3 °C
    Vapour Pressure9.65E-08mmHg at 25°C
    Refractive index1.618
    SMILESC(S(=O)(=O)N1CCCC1)C2=CC=C(N)C=C2
    InChI KeyInChIKey=VNSKHALYBQZMFW-UHFFFAOYSA-N


      About Packaging  


    Storage

    Should be stored in a cool, dry, and well-ventilated place. It should also be kept in a tightly closed container and locked up to prevent unauthorized access.


    Package

    50kg/bag or as per your particular request.

    Certificates

    Basic Info
    Product Name:

    4-[(1-Pyrrolidinylsulfonyl)methyl]benzenamine

    Other Name:

    Benzenamine,4-[(1-pyrrolidinylsulfonyl)methyl]-;Pyrrolidine,1-[[(4-aminophenyl)methyl]sulfonyl]-;4-[(1-Pyrrolidinylsulfonyl)methyl]benzenamine;1-((4-Aminobenzenemethane)sulfonyl)pyrrolidine

    CAS No.:

    334981-10-1

    Molecular Formula:

    C11H16N2O2S

    InChIKeys:

    InChIKey=VNSKHALYBQZMFW-UHFFFAOYSA-N

    Molecular Weight:

    240.32194

    Exact Mass:

    240.32

    EC Number:

    1308068-626-2

    DSSTox ID:

    DTXSID80458020

    HScode:

    2935009090

    Characteristics
    PSA:

    71.8

    XLogP3:

    0.76

    Appearance:

    Pale yellow solid

    Density:

    1.3±0.1 g/cm3

    Melting Point:

    170-176°C

    Boiling Point:

    434.2±47.0 °C at 760 mmHg

    Flash Point:

    216.4±29.3 °C

    Refractive Index:

    1.618

    Storage Conditions:

    Refrigerator

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Flavor & Fragrance Ingredients,Plasticizer,API,Pharmaceutical Intermediates,Thermal Powder,Plant Extract

    Location:

    Room 902, 917, Hua Teng Bei Tang Business Plaza, No.37 Nan Mo Fang Road, Chao Yang District, Bei Jing, China

    Payment Terms:

    L/C,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2001

    Beijing Entrepreneur Science & Trading Co., Ltd. was established in the year 2001. We are focused on import and export business of high quality specialty chemicals. Since its establishment, relying on diligent efforts, spirit of enterprising and professional services, the company has established extensive cooperation with world-famous chemical manufacturers and gained a good reputation in China chemical industry.

    We have stable distribution cooperation with world leading suppliers from America, Europe, Japan and Taiwan. We are distributors of Ames Advantage Material, Novamet, Lanxess, Momentive, Potters, Rhodia, Roquette, Oerlikon Metco, Inovyn, KJ Chemical, Tokuyama, Mitsubishi Chemical, Chang Chun Group, etc.

    Our products selling in China include Conductive Powder, Thermal Conductive Powder, Microwave Absorbing Powder, Acrylamide Functional Monomer and Special UV Monomer, Special Epoxy Resin, Mercaptan Curing Agent, Silane, Fumed Silica and Precipitated Silica, PVC Paste Resin, PVA, Carbon Black, Modified Starch, Photocatalyst, Formaldehyde Capture agent, Root Blocking Agent, Platinum Catalyst, Vinyl Silicone Oil, Surfactant, etc

    In 2014, the company entered the chemical export business. Based on our understanding of China chemical market, we select most qualified suppliers. We are able to source raw materials directly from factories. Most of our partners are the largest factory in China with over 20 years history. They have huge annual outputs, and hold ISO9001, ISO14001, GMP, KOSHER, HALAL, FDA, GSP, etc. certificates.

    Our export products include Conductive Powder, Thermal Conductive Powder, Plant Extract, Inorganic Powder, Plasticizer, PVC Paste Resin, Silane, Flavors and Fragrances, Salen Catalysts and Ligands, Organic Intermediates, Pharmaceutical Intermediates.

    We continue to add new product lines and chemical distribution centers to service a wider range of industries.

    We hope to become a bridge between China chemical manufacturers and world-wide customers, continue to provide professional products and solutions for customers overseas. We look forward to considerable development in export business of specialty chemicals.

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