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Finerenone, CAS No.: 1050477-31-0 buy - large image1
Finerenone, CAS No.: 1050477-31-0 buy - image1

Finerenone, CAS No.: 1050477-31-0

TDS 17 Inquiries

Unit Price: Get Latest Price
CAS No.:

1050477-31-0

Grade:

Pharmaceutical Grade

Content:

98%

Port:

Beijing

Brand:

HANDOM CHEM

Packaging:

1kg/bag or according to the specific requirements from customers

Price valid (until):

2023-11-08

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Details  


    Finerenone is a nonsteroidal selective mineralocorticoid receptor antagonist that has been shown in preclinical studies to block the deleterious effects of mineralocorticoid receptor overactivation. In patients with diabetes, overactivation of mineralocorticoid receptors is thought to contribute to chronic kidney disease progression and cardiovascular impairment, which may be driven by factors such as metabolism, hemodynamics, or inflammation and fibrosis.

    Test ItemsSpecifications
    Appearance

    White or off-white powder

     

    Identification

    The retention time of test sample major peak complies to reference standard.

    The IR absorption spectrum of the test sample complies to reference standard.

    Loss on Drying

    Not more than 1.0%

     

    Related Substances


    Single impurity: ≤0.1%

    Total impurities: ≤1.0%

    Enantiomer

    Not more than 0.1%

    Residue on Ignition

    Not more than 0.1%

    Heavy Metals

    Not more than 20 ppm






    Residual Solvents







    Ethanol: ≤5000 ppm

    Toluene: ≤890 ppm

    Tetrahydrofuran: ≤720 ppm

    Acetonitrile: ≤410 ppm

    tert-Butyl methyl ether: ≤5000 ppm

    Ethyl acetate: ≤5000 ppm

    Assay(on the anhydrous basis)

    98.0% ~ 102.0%

    Indications:
    For use in adults with chronic kidney disease associated with type 2 diabetes (estimated glomerular filtration rate [eGFR] 25 to <75 mL/min/1.73 m2 with albuminuria) to reduce persistent eGFR decline, end-stage Risk of kidney disease.

    Pharmacological Effects:
    This drug is a nonsteroidal, selective mineralocorticoid receptor (MR) antagonist. MR is expressed in the kidney, heart, and blood vessels, and fenelinone can reduce inflammation and fibrosis mediated by MR overactivation.

    Certificates

    Basic Info
    Product Name:

    Finerenone

    Other Name:

    Finerenone (BAY 94-8862);(4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide;BAY 94-8862;BAY948862;1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-, (4S)-;Finerone;Mr Neri ketone;(S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide

    CAS No.:

    1050477-31-0

    Molecular Formula:

    C21H22N4O3

    InChIKeys:

    BTBHLEZXCOBLCY-QGZVFWFLSA-N

    Molecular Weight:

    378.42

    Exact Mass:

    378.42

    Color/Form:

    White to off-white

    Characteristics
    λmax:

    255 nm

    Density:

    1.29±0.1 g/cm3(Predicted)

    Boiling Point:

    554.7±50.0 °C(Predicted)

    PKA:

    14.76±0.40(Predicted)

    Critical Temperature & Pressure:

    -20°C

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

    Location:

    RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

  • Inquiry History
    17 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Finerenone 95%

    10.00 KG Sep 10, 2025
    Pakistan

    Finerenone

    2 KG Mar 18, 2026
    Pakistan

    Finerenone

    10 G Jan 14, 2026
    Pakistan

    Finerenone

    1 KG Dec 4, 2025
    Bangladesh

    Finerenone

    50 KG Dec 1, 2025
    Pakistan

    Finerenone

    1 KG Jun 28, 2024
    Pakistan

    FINERENONE

    200 G Jun 3, 2026
    Pakistan

    Finerenone

    13 KG Jul 22, 2024
    India

    Finerenone

    50 KG Jan 3, 2024
    India

    Finerenone

    1.00 KG Dec 19, 2023
    India

    Finerenone

    1.00 KG Dec 11, 2023
    Indonesia

    Finerenone api

    1 KG Oct 7, 2023
    Palestine

    Finerenone 1050477-31-0

    1 KG Mar 17, 2025
    India

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