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t-Butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate

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CAS No.:

1236033-21-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Beijing

Packaging:

25kg/drum

Sample Available:

Yes

Price valid (until):

2023-11-09

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Jinan Million Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

L/C,100% TT in advance

Average Lead Time:

3 days

Qualification:

Main Products:

Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

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Product Details
Seller Information

Description

Baricitinib intermediate,

Million pharm is manufacture and supply Baricitinib as API (Active Pharmaceutical Ingredient), including baricitinib intermediates.

Baricitinib, (api power manufactured by Million pharm) sold under the brand name Olumiant among others, is an immunomodulatory medication used for the treatment of rheumatoid arthritis, alopecia areata, and COVID-19

In June 2022, U.S. FDA approved Olumiant (baricitinib) oral tablets to treat adult patients with severe alopecia areata. Alopecia areata is a disorder that often appears as patchy baldness and affects more than 300,000 people in the U.S. every year.

Baricitinib is a Janus kinase (JAK) inhibitor that reversibly inhibits Janus kinase 1 with a half maximal inhibitory concentration (IC50) of 5.9 nM and Janus kinase 2 with an IC50 of 5.7 nM.

Basic Info

Product Name:
tert-butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate

Other Name:
tert-butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate;7H-Pyrrolo[2,3-d]pyrimidine-7-carboxylic acid, 4- chloro-, 1,1-dimethylethyl ester;t-Butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate;tert-butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate;ert-butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate;4-Chloropyrrolo[2,3-d]pyrimidine-7-carboxylic acid tert-butyl ester;4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid tert-butyl ester;4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid 1,1-dimethylethyl ester

CAS No.:
1236033-21-8

Molecular Formula:
C11H12ClN3O2

InChIKeys:
XGGUTWYJGILAOA-UHFFFAOYSA-N

Molecular Weight:
253.68

Exact Mass:
253.062

EC Number:
152-854-1

Categories:
Bulk Drug Intermediates

Characteristics

PSA:
57.01

XLogP3:
2.8679

Density:
1.34±0.1 g/cm3(Predicted)

Boiling Point:
363.1±45.0 °C(Predicted)

PKA:
2.33±0.30(Predicted)

Critical Temperature & Pressure:
-20°C, sealed storage, away from moisture
Seller Information

Business Type:
Manufactory

Main Products:
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

Location:
Room 1-2208, Lianhecaifu Square, No2177, Tianchen Road, Gaoxin District, Jinan City, Shandong Province, China

Payment Terms:
L/C,100% TT in advance

Average lead Time:
3 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2012

Company Certificates
- business license
Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixaban, Lurasidone, Bexagliflozin, Votioxitine, Loxo-292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; INCETPAT PHARM; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.
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Product Name	Grade / Content	Price	Supplier Name	Details
Top Quality Baricitinib Intermediate in Bulk CAS 1236033-21-8	Pharmaceutical grade/99		NATURE INDUSTRIAL LIMITED	Inquiry
tert-butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate 1236033-21-8	Pharmaceutical Grade/99		Hangzhou Zentra Bio-Chemical Co., Ltd.	Inquiry

t-Butyl 4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate

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