100% Safe Delivery High Quality Price 49562-28-9 raw Fenofibrate powder
KOSHER ISO FDA 5 Inquiries
49562-28-9
Food grade
99%
shenzhen
Flying
10g/1kg/ 10kg/ 25kg
2023-11-12
vitamin
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceFenofibrate is a PPARα agonist with an EC50 of 30 μM.
Solid
Fenofibrate is a chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring. It has a role as an antilipemic drug, an environmental contaminant, a xenobiotic and a geroprotector. It is a chlorobenzophenone, a member of monochlorobenzenes, an aromatic ether and an isopropyl ester. It derives from a benzophenone.|Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia. Fenofibrate was granted FDA approval on 31 December 1993.|Fenofibrate is a Peroxisome Proliferator Receptor alpha Agonist. The mechanism of action of fenofibrate is as a Peroxisome Proliferator-activated Receptor alpha Agonist.|Fenofibrate is a fibric acid derivative used in the therapy of hypertriglyceridemia and dyslipidemia. Fenofibrate therapy is associated with mild and transient serum aminotransferase elevations and with rare instances of acute liver injury, which can be severe and prolonged and lead to significant hepatic fibrosis.|Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. Fenofibrate is hydrolyzed in vivo to its active metabolite fenofibric acid that binds to and activates peroxisome proliferator activated receptor alpha (PPARalpha), resulting in the activation of lipoprotein lipase and reduction of the production of apoprotein C-III, an inhibitor of lipoprotein lipase activity. Increased lipolysis and a fall in plasma triglycerides, in turn, leads to the modification of the small, dense low density lipoporotein (LDL) particles into larger particles that are catabolized more rapidly due to a greater affinity for cholesterol receptors. In addition, activation of PPARalpha also increases the synthesis of apoproteins A-I, A-II, and high density lipoprotein (HDL)-cholesterol. Overall, fenofibrate reduces total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) while increasing HDL cholesterol.|An antilipemic agent which reduces both CHOLESTEROL and TRIGLYCERIDES in the blood.CertificatesBasic Info-
Product Name:
Fenofibrate
Other Name:Propanoic acid,2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-,1-methylethyl ester;Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate;LF 178;Lipanthyl;Procetofen;Fenofibrate;TriCor;Lipantil;Lipirex;Fenogal;Lipofene;Lipoclar;Lipidil;Secalip;Lipsin;Elasterin;Ankebin;Protolipan;Liposit;Procetofene;Nolipax;Procetoken;Fenobrate;Fenotard;NSC 281319;Lipidil Supra;Clorofibrate;Antara;MeltDose;Lipicard;Lipivim;Fenorate;Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate;Lipanthylnano
CAS No.:49562-28-9
Molecular Formula:C20H21ClO4
InChIKeys:InChIKey=YMTINGFKWWXKFG-UHFFFAOYSA-N
Molecular Weight:360.83
Exact Mass:360.83
EC Number:256-376-3
UNII:U202363UOS
NSC Number:757822|281319
DSSTox ID:DTXSID2029874
NCI Thesaurus Code:C29047
Color/Form:Crystals from isopropanol|White solid
ATC Code:C10BA04|C10BA03|C10AB05|C - Cardiovascular system
HScode:2932999099
Categories:
Characteristics-
PSA:
52.6
XLogP3:5.2
Appearance:off-white powder
Density:1.2±0.1 g/cm3
Melting Point:80.5 °C
Boiling Point:469.8ºC at 760 mmHg
Flash Point:165.4±24.9 °C
Refractive Index:1.547
Water Solubility:H2O: 0.25mg/ml at 25 °C
Storage Conditions:Store at RT
Vapor Pressure:6.2X10-7 mm Hg at 25 deg C (est)
Toxicity:LD50 in mice: 1600 mg/kg orally (Sornay)
Henrys Law Constant:Henry's Law constant = 4.5X10-9 atm-cu m/mol at 25 °C (est)
Collision Cross Section:190.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Stable under ordinary conditions|Hydroxyl radical reaction rate constant = 2.5X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Specific target organ toxicity â repeated exposure, Category 2
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H373 May cause damage to organs through prolonged or repeated exposure
H413 May cause long lasting harmful effects to aquatic life
Precautionary statement(s) Prevention P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
Response P319 Get medical help if you feel unwell.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store at 25 deg C (77 deg F); excursions permitted to 15-30 deg C (59-86 deg F). ... Protect from moisture.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted
Indonesia
100% Safe Delivery High Quality Price CAS: 49562-28-9 raw Fenofibrate powder
10 G Sep 30, 2023
India
Fenofibrate
160 MG May 29, 2026
India
NANO FENOFIBRATE
10.00 KG Sep 2, 2024
Indonesia
Raw Fenofibrate Powder
10 G Sep 30, 2023
Philippines
Fenofibrate 99% white
1 KG Jan 4, 2024 Post an enquiry for this product
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