Product
Supplier
Encyclopedia
Inquiry
Home > Pharmaceutical Intermediates > Antidementia Agents > Ethosuximide for Sale > 3-Ethyl-3-Methyl-;Ethosuximide solution
3-Ethyl-3-Methyl-;Ethosuximide solution buy - large image1
3-Ethyl-3-Methyl-;Ethosuximide solution buy - image1

3-Ethyl-3-Methyl-;Ethosuximide solution

3 Inquiries

Unit Price: Get Latest Price
CAS No.:

77-67-8

Port:

SHANGHAI

Packaging:

1kg/BAG

Price valid (until):

2023-11-16

Company Type:
Manufactory
Location:
China
Payment Terms:
D/P,L/C,D/A
Average Lead Time:
15 days
Qualification:
Main Products:

Dichloromethane,Linocaine hydrochloride

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


     The antiepileptic drug ethosuximide rescued the short lifespan and chemoinduction defects of C. elegans DNJ-14 ineffective mutants. It also improves dyskinesia and short lifespan in worms that express human-derived Tau mutants that cause frontotemporal dementia. Ethosuximide plays a life-prolonging role by inhibiting specific chemo-induced neurons. In rats with a phenotype similar to Alzheimer's disease, it promotes nerve regeneration, reduces neurodegeneration, and alters cognitive impairment.


    Pls input...

    ItemsSpecifications






    ECHEMI Editorial Reference
    Ethosuximide, a widely prescribed anti-epileptic drug, improves the phenotypes of multiple neurodegenerative disease models and blocks the low voltage activated T-type calcium channel.
    Solid
    Ethosuximide is a dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures. It has a role as an anticonvulsant, a calcium channel blocker and a geroprotector. It is a pyrrolidinone and a dicarboximide.|An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.|Ethosuximide is an succinimide based anticonvulsant commonly used for absence (petit mal) seizures in both adults and children. Ethosuximide has been associated with rare instances of serum enzyme elevations during treatment, but has not been linked to cases of clinically apparent liver injury with jaundice.|Methsuximide is a succinimide-based anticonvulsant similar to ethosuximide that is used for absence (petit mal) seizures in both adults and children. Methsuximide was associated with hepatic injury in experimental animals, but has not been linked to serum enzyme elevations during treatment or to cases of clinically apparent liver injury with jaundice.

    Basic Info
    Product Name:

    Ethosuximide

    Other Name:

    2,5-Pyrrolidinedione,3-ethyl-3-methyl-;Succinimide,2-ethyl-2-methyl-;3-Ethyl-3-methyl-2,5-pyrrolidinedione;C.I. 366;PM 671;Emeside;Ethosuxide;Ethosuximide;3-Ethyl-3-methylpyrrolidine-2,5-dione;2-Ethyl-2-methylsuccinimide;Petinimid;Petnidan;Succimitin;Suxinutin;Zarodan;Zarondan-Saft;Zarontin;α-Ethyl-α-methylsuccinimide;Simatin;Ronton;3-Methyl-3-ethylpyrrolidine-2,5-dione;Pyknolepsinum;Succimal;Capitus;Atysmal;Ethymal;Pemal;Mesentol;Suxilep;Suximal;Etosuximid;Piknolepsin;H 940;Zarondan;3-Ethyl-3-methylsuccinimide;α-Methyl-α-ethylsuccinimide;3-Methyl-3-ethylsuccinimide;2-Methyl-2-ethylsuccinimide;Epileo Petitmal;CN 10395;Peptinimid;NSC 64013;(±)-Ethosuximide;8060-73-9;39122-18-4

    CAS No.:

    77-67-8

    Molecular Formula:

    C7H11NO2

    InChIKeys:

    InChIKey=HAPOVYFOVVWLRS-UHFFFAOYSA-N

    Molecular Weight:

    141.17

    Exact Mass:

    141.17

    EC Number:

    201-048-7

    NSC Number:

    758192|64013

    DSSTox ID:

    DTXSID7023019

    Color/Form:

    Crystals from acetone and ether|WHITE TO OFF-WHITE CRYSTALLINE POWDER OR WAXY SOLID

    ATC Code:

    N03AD01|N - Nervous system

    HScode:

    2925190090

    Categories:

    Antidementia Agents

    Characteristics
    PSA:

    46.2

    XLogP3:

    0.4

    Appearance:

    Solid

    Density:

    1.1±0.1 g/cm3

    Melting Point:

    64.5 °C

    Boiling Point:

    129 °C

    Flash Point:

    123.8±18.9 °C

    Refractive Index:

    1.451

    Water Solubility:

    ethanol: 100 mg/mL

    Storage Conditions:

    Refrigerator

    Vapor Pressure:

    5.43X10-7 mm Hg at 25 deg C (est)

    Toxicity:

    LD50 in mice (g/kg): 1.65 i.p.; 1.75 orally (Najer)

    Odor:

    CHARACTERISTIC ODOR

    Henrys Law Constant:

    Henry's Law constant = 5.93X10-8 atm-cu m/mol at 25 °C (est)

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 1.16X10-11 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Ethosuximide capsules should be stored in tight containers at a temperature less than 30 deg C, preferably between 15-30 deg C. Ethosuximide oral solution should be stored in tight, light-resistant containers at a temperature less than 30 deg C, preferably between 15-30 deg C; freezing should be avoided.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Dichloromethane,Linocaine hydrochloride

    Location:

    BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA

    Payment Terms:

    D/P,L/C,D/A

    Average lead Time:

    15 days

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    11-50

    Year of Establishment:

    2016

    Shandong zhishang chemical Co.,Ltd is a leading Manufactory supplier of Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1), Ethylene oxide-propylene oxide copolymer, Strontium carbonate based in Jinan, Shandong, China. With a commitment to quality and customer satisfaction, Shandong zhishang chemical Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1), Ethylene oxide-propylene oxide copolymer, Strontium carbonate, which are available at competitive prices. Shandong zhishang chemical Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    Russia

    High Quality 99% Purity of EthosuxiMide CAS NO 77-67-8 ISO 9001:2005 REACH Verified Producer

    20 KG Oct 14, 2023
    Egypt

    Ethosuximide

    5 KG Jun 19, 2025
    Russia

    Ethosuximide

    10 KG Oct 14, 2023
    Post an enquiry for this product
pic ×

Scan the QR Code to Share

All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.

According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

The information shown above is provided by the enterprise itself, and the authenticity, accuracy and legitimacy of the content are the responsibility of the publishing company. ECHEMI does not bear any guarantee responsibility for this. Please be aware that risks in internet transactions objectively exist.

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.