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L-Carnosine, CAS No.: 305-84-0

Name: L-Carnosine, CAS No.: 305-84-0
Brand: HANDOM CHEM
SKU: pr2311051008
Price: 155 USD
Availability: InStock

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CAS No.:

305-84-0

Grade:

Cosmetics Grade

Content:

99%

Port:

Shanghai or Beijing

Brand:

HANDOM CHEM

Packaging:

1Kg/Aluminum Foil Bag; 20Kg/Fibre Drum

Price valid (until):

2023-12-05

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DALIAN HANDOM CHEMICALS CO.,LTD.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Brief Introduction:
L-Carnosine, scientific name β-alanyl-L-histidine, is a crystalline solid dipeptide composed of two amino acids: β-alanine and L-histidine. Muscle and brain tissue contain high concentrations of carnosine.

Studies in the UK, South Korea, Russia and other countries have shown that carnosine has strong antioxidant capacity and is beneficial to the human body. Carnosine has been shown to scavenge reactive oxygen species (ROS) and α-β unsaturated aldehydes formed during oxidative stress by excessive oxidation of fatty acids in cell membranes.

Test Items	Specifications
Appearance	White or off-white powder
HPLC Identification	The retention time of the main peak is consistent with the reference substance
pH Value	7.5 ~ 8.5
Lead(Pb)	Not more than 1 ppm
Arsenic(As)	Not more than 1 ppm
Cadmium(Cd)	Not more than 1 ppm
Mercury(Hg)	Not more than 0.1 ppm
Loss on Drying	Not more than 1.0%
Residue on Ignition	Not more than 0.1%
L-His	Not more than 0.3%
Specific Rotation	+20.0° ~ +22.0°
Purity(HPLC)	Not less than 99.0%
Assay	99.0% ~ 101.0%
Total Aerobic Microbial Count	Not more than 1000 CFU/g
Total Yeasts & Moulds Count	Not more than 100 CFU/g
Thermotolerant coliform	Negative
Pseudomonas aeruginosa	Negative
Staphylococcus aureus	Negative
Salmonella	Negative

Shop L-Carnosine, CAS No.: 305-84-0-Detailed Image 1

Applications:
1. New food additive;

2. L-Carnosine has a significant inhibitory effect on lipid oxidation caused by free radicals and metal ions. In meat processing, carnosine has the effect of inhibiting fat oxidation and protecting meat color. Carnosine and phytic acid resist oxidation of beef. Adding 0.9g/kg carnosine to the diet can improve meat color and increase the oxidative stability of skeletal muscle, and it also has a synergistic effect with vitamin E;

3. Use in cosmetics: It can prevent skin aging and has the effect of skin whitening;

4. It can enhance the light transmittance of turbid human eye lenses: Senile cataracts can be treated with antioxidant preparations based on carnosine;

5. Sensors of olfactory nerves: Oral drugs that can promote wound healing and are especially used in surgical treatments.

Packaging:
1kg/Aluminum foil bag, 20kg/Drum or 25kg/Drum.

Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

Shelf Life:
24 months if stored under above mentioned conditions.

ECHEMI Editorial Reference

Crystalline
Solid
Carnosine is a dipeptide that is the N-(beta-alanyl) derivative of L-histidine. It has a role as an anticonvulsant, an antioxidant, an antineoplastic agent, a human metabolite, a Daphnia magna metabolite, a mouse metabolite, a neuroprotective agent and a geroprotector. It is a conjugate acid of a carnosinate. It is a tautomer of a carnosine zwitterion.|Carnosine has been investigated for the treatment of Gulf War Illness.|Carnosine is a dipeptide comprised of a beta-alanine and a 3-methyl-L-histidine, which is found in dietary red meat, with potential antioxidant, metal-chelating and anti-glycation activities. Carnosine scavenges both reactive oxygen species (ROS) and unsaturated aldehydes produced by cell membrane lipid peroxidation. Additionally, this dipeptide may reduce the rate of formation of advanced glycation end-products (AGE). Altogether, this may protect cells against oxidative damage. In addition, carnosine is able to chelate toxic metals.|A naturally occurring dipeptide neuropeptide found in muscles.
L-Carnosine is a dipeptide composed of β-alanine and L-histidine that has been found in rat olfactory bulb, skeletal muscle, brain, kidney, and spleen tissues, as well as human skeletal muscle, and has diverse biological activities. It is a metal chelator that forms complexes with copper, cobalt, nickel, cadmium, or zinc. Dietary administration of L-carnosine (60 mg/kg per day) reduces plasma levels of advanced glycation end products (AGEs) in diabetic rats. It reduces brain edema, blood-brain barrier disruption, microglial activation, and neuronal apoptosis in a rat model of intracerebral hemorrhage when administered at a dose of 1,000 mg/kg. L-Carnosine (250, 500, and 1,000 mg/kg, i.p.) reduces hepatic protein carbonylation and necrosis in a rat model of cirrhosis induced by bile duct ligation. It also reduces lung myeloperoxidase (MPO) activity, production of reactive oxygen species (ROS), and TNF-α and IL-6 levels, as well as alveolar hemorrhage, interstitial edema, and pulmonary leukocyte infiltration in a mouse model of LPS-induced lung injury.
white to off-white crystalline.

Certificates

Basic Info

Product Name:

L-Carnosine

Other Name:

N-B-ALANYL-L-HISTIDINE;H-BETA-ALA-HIS-OH;L-IGNOTINE;L-BETA-ALANINE HISTIDINE;L-CARNOSINE;B-ALANYL-L-HISTIDINE;BETA-A-H;BETA-ALANYL-L-HISTIDINE

CAS No.:

305-84-0

Molecular Formula:

C9H14N4O3

InChIKeys:

CQOVPNPJLQNMDC-ZETCQYMHSA-N

Molecular Weight:

226.23

Exact Mass:

226.23

BRN:

87671

EC Number:

206-169-9

UNII:

8HO6PVN24W

TSCA:

TSCA listed

DSSTox ID:

DTXSID7048615

NCI Thesaurus Code:

C118880

Color/Form:

White

HScode:

29332900

Categories:

Polypeptide

Characteristics

PSA:

121

XLogP3:

-4

Appearance:

White crystalline

Density:

1.2673 (rough estimate)

Melting Point:

253 °C (dec.) (lit.)

Boiling Point:

367.84°C (rough estimate)

Flash Point:

350.7ºC

Refractive Index:

21 ° (C=2, H2O)

Water Solubility:

almost transparency

Storage Conditions:

2-8°C

Vapor Pressure:

0Pa at 25℃

Toxicity:

LD50 oral in mouse: > 14930mg/kg

Flammability characteristics:

Thermal decomposition to emit toxic nitrogen oxide fumes

Specific rotation:

20.9 º (c=1.5, H2O)

Odor:

at 100.00%. odorless

PKA:

2.62(at 25℃)

Collision Cross Section:

151 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|149.72 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|152.18 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|154.1 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|154.93 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|150.8 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|154.7 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|152.1 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|153.1 Å² [M-H]-

Critical Temperature & Pressure:

-20°C

See More L-Carnosine Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More L-Carnosine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2020

Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

Inquiry History

42 Inquiries

Country	Product	Purchase Quantity	Date Posted
Russia	L-Carnosine CAS 305-84-0	50 KG	Jan 13, 2026
India	L-Carnosine	20.00 MT	Dec 13, 2023
India	L-Carnosine	10.00 KG	Dec 12, 2023
India	L-Carnosine	1.00 KG	Oct 11, 2025
India	L-Carnosine	10.00 MT	Dec 15, 2023
India	L-Carnosine	20.00 MT	Dec 13, 2023
Australia	L-Carnosine	1000 G	Aug 4, 2026
India	L-Carnosine	1 KG	Aug 4, 2026
India	L-Carnosine	100 KG	Jul 10, 2026
India	L-Carnosine	25.00 KG	Jun 29, 2026
India	L-Carnosine	1.00 KG	Jun 4, 2026
India	L-Carnosine	1.00 KG	May 28, 2026
India	L-Carnosine	25.00 KG	Mar 9, 2026
India	L- Carnosine	150.00 KG	Jan 21, 2026
India	L-Carnosine	500.00 KG	May 30, 2025
Australia	L-Carnosine	1 KG	Sep 30, 2024
Russia	carnosine L	100 KG	Mar 11, 2024
Hungary	L-Carnosine	1 KG	Jul 6, 2026
Netherlands	L-Carnosine	15 KG	Jun 24, 2026
India	L-Carnosine	1.00 KG	May 28, 2026

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