2 6-pipecoloxylidide or 2',6'-Pipecoloxylidide,2', 6'- piperidine peroxide

Intermediates of Roper and Bupivacaine,

Pipecolinoyl-2,6-xylidide;N-(2',6'-dimethylphenyl)-piperidine-2-carboxylicamide;Des-butylBupivacaine(Bupivacainemetabolite);Desbutylbupivacain;N-(2'Chemicalbook,6'-Dimethylphenyl)-2-Pip;(2RS)-N-(2,6-DIMETHYLPHENYL)-2-PIPERIDINECARBOXAMIDE;2',6'-Pipecoloxylidide;N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide

Keep in dark place,Sealed in dry,2-8°C

Chloroform (Slightly), Methanol (Slightly)

White to Almost white

392.3±42.0 °C(Predicted)

N-(2',6'-xylyl)-2-piperidinecarboxamide is mainly used to synthesize bupivacaine, which is a long-acting amide local anesthetic and is suitable for peripheral nerve block and dura mater treatment. External block and subarachnoid block. Its hydrochloride is commonly used and is a white crystalline powder, odorless and bitter in taste. The local anesthetic effect is stronger than lidocaine (about 4 times stronger). The time for its Chemicalbook 0.25%-0.5% solution to induce local anesthesia is generally 4-10 minutes, while the 0.75% solution takes effect slightly faster. Use its 0.5% solution plus epinephrine for epidural anesthesia, and the effect can last for 5 hours. Because this product has a low concentration in the blood, little accumulation in the body, and a long duration of action, it is a safer long-acting local anesthetic.

Intermediates of Roper and Bupivacaine