Hypericin, CAS:548-04-9
2 Inquiries
548-04-9
Reagent Grade
99%
Guangzhou
BTO
g
2029-12-31
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceHypericin is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum. It can inhibit tyrosine kinases with IC50 of 7.5 μM. IC50: 7.5 uMIn vitro:The photosensitive of hypericin can induce both apoptosis and necrosis in a concentration and light dose-dependent fashion. PDT with hypericin results in the activation of multiple pathways that can either promote or counteract the cell death program. It can effect cytotoxic to tumor cells by visible
Hypericin is a carbopolycyclic compound. It has a role as an antidepressant. It derives from a hydride of a bisanthene.|Hypericin is an anthraquinone derivative that is naturally found in the yellow flower of Hypericum perforatum (St. John's wort) with antidepressant, potential antiviral, antineoplastic and immunostimulating activities. Hypericin appears to inhibit the neuronal uptake of serotonin, norepinephrine, dopamine, gamma-amino butyric acid (GABA) and L-glutamate, which may contribute to its antidepressant effect. Hypericin may also prevent the replication of encapsulated viruses probably due to inhibition of the assembly and shedding of virus particles in infected cells. This agent also exerts potent phototoxic effects by triggering apoptotic signaling that results in formation of reactive oxygen species.Basic Info-
Product Name:
Hypericin
Other Name:Phenanthro[1,10,9,8-opqra]perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-,stereoisomer;stereoisomer of 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione;Cyclosan;Cyclo-Werol;Hypericin;Hypericum red;1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione P-conformer;NSC 407313;Hyperflav;345224-62-6;935869-37-7;693273-27-7
CAS No.:548-04-9
Molecular Formula:C30H16O8
InChIKeys:InChIKey=BTXNYTINYBABQR-UHFFFAOYSA-N
Molecular Weight:504.44
Exact Mass:504.44
BRN:1917913
EC Number:208-941-0
UNII:7V2F1075HD
NSC Number:622946|407313
DSSTox ID:DTXSID40203270
NCI Thesaurus Code:C37456
HScode:2914700090
Categories:
Characteristics-
PSA:
156
XLogP3:8.39
Appearance:black powder
Density:1.9±0.1 g/cm3
Melting Point:299-301°C
Boiling Point:930.1±65.0 °C at 760 mmHg
Flash Point:530.1±30.8 °C
Refractive Index:2.131
Water Solubility:soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide. Insoluble in water.1 M NaOH: 10 mg/mL
Storage Conditions:Store at +4°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Skin sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H317 May cause an allergic skin reaction
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2021
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Austria
hypericin 99% brown powder Factory Supply CAS 548-04-9 hypericin
50 G Nov 10, 2023
United States
Hypericine
500 G May 16, 2025 Post an enquiry for this product