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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > alpha-Arbutin for Sale > China Most Professional Manufacturer Supply High Qulity Alpha Arbutin CAS 84380-01-8
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China Most Professional Manufacturer Supply High Qulity Alpha Arbutin CAS 84380-01-8

GMP HALAL KOSHER ISO FDA TDS 38 Inquiries

Unit Price: Get Latest Price
CAS No.:

84380-01-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Leader

Packaging:

25KG/Drum

Sample Available:

Yes

Price valid (until):

2023-12-26

Company Type:
Manufactory
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
5 days
Qualification:
Main Products:

Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      About Product Technical Details  


    alpha-Arbutin Chemical Properties
    Melting point  195-196°C
    Boiling point  561.6±50.0 °C(Predicted)
    density  1.556±0.06 g/cm3(Predicted)
    storage temp.  2-8°C
    solubility  DMSO (Slightly), Methanol (Slightly)
    form  Solid
    pka 10.10±0.15(Predicted)
    color  White to Off-White
    BRN  89675
    InChI InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/s3
    InChIKey BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
    SMILES O(C1C=CC(O)=CC=1)[C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:8,9,10,12,14,r|
    CAS DataBase Reference 84380-01-8(CAS DataBase Reference)

    Safety Information
    WGK Germany  3
    HS Code  2938.90.0000


      Product Pictures  


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      About Our Group


            Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture high quality raw materials and refined ingredients which is widely used at different industries areas like Pharm & chemicals industry, functional active ingredients industry, nutritional Ingredients industry, health care products industry, cosmetics industry,  pharmaceutical and refined food, feed, oil industry, natural plant ingredients industries, agriculture industry etcs to provide top quality of GMP standards products.

            All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, agriculture raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China.

            Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates.

           With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people.

           We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  

           We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.



      Our Factories Production Lines  



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      Sales Team  


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    ECHEMI Editorial Reference
    α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is emerging as popular and effective skin whiteners, acting as tyrosinase inhibitor[1].
    Alpha-Arbutin is a glycoside.
    Arbutin is naturally found in plant sources such as Bearberry, Cranberry and Mulberry, which essentially prevents the formation of melanin (the pigment that creates skin colour). The chemically synthesised version of this plant extract is known as Alpha Arbutin which is used as a topical skin brightening agent to treat sun spots, pigmentation and scars caused by sun damage and breakouts. It also has antioxidant properties, which protect the skin from potential sun damage. Along with Retinol, it is a fairly common ingredient in anti-ageing products to treat age spots, fine lines and wrinkles.
    It is a glycosylated hydroquinone molecule, meaning a sugar molecule that has replaced one of the hydroxyl (-OH) groups on hydroquinone. Hydroquinone is seen as the gold standard of skin lightening, but there are concerns surrounding this well-studied tyrosinase inhibitor, such as skin sensitization, melanocytotoxicity from oxidative byproducts, and exogenous ochronosis (blue-black splotchy pigmentation) as a result of long-term application.1,2 Alpha arbutin is a more tolerable alternative to hydroquinone and is sometimes referred to as “natural hydroquinone.” Alpha arbutin functions similarly to hydroquinone, due to its molecular structure, but with reduced irritation and melanocytotoxicity. Alpha arbutin does not pose a risk in regards to exogenous ochronosis and poses minimal irritation and sensitization risk, making it a more tolerable alternative to hydroquinone.
    Arbutin is the best as compared to vitamin c because it has fewer side effects and more benefits like reducing dark spots, age spots, ageing, etc. Arbutin gives quicker results than vitamin C. Arbutin acts as hydroquinone, which means it has depigmenting factors. Vitamin C is not easily absorbed into the skin, whereas arbutin absorbs quickly into the skin.

    Certificates
    • China Most Professional Manufacturer Supply High Qulity Alpha Arbutin  CAS 84380-01-8 Certificates 7 TDS

    Basic Info
    Product Name:

    alpha-Arbutin

    Other Name:

    4-hydroquinone-alpha-d-glucopyranoside;alpha-arbutin;a-Arbutin;Hydroquinone O-α-D-Glucopyranoside;4-Hydroxyphenyl a-D-glucopyranoside;(2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL;4-hydroxyphenyl alpha-D-glucopyranoside;Alpha bear

    CAS No.:

    84380-01-8

    Molecular Formula:

    C12H16O7

    InChIKeys:

    BJRNKVDFDLYUGJ-ZIQFBCGOSA-N

    Molecular Weight:

    272.25

    Exact Mass:

    272.25

    BRN:

    89675

    EC Number:

    209-795-0

    UNII:

    72VUP07IT5

    DSSTox ID:

    DTXSID20233358

    Color/Form:

    White to Off-White

    HScode:

    2938.90.0000

    Characteristics
    PSA:

    120

    XLogP3:

    -0.7

    Appearance:

    White Crystalline powder

    Density:

    1.556±0.06 g/cm3(Predicted)

    Melting Point:

    195-196°C

    Boiling Point:

    561.6±50.0 °C(Predicted)

    Flash Point:

    293.4±30.1 °C

    Refractive Index:

    1.650

    Storage Conditions:

    2-8°C

    PKA:

    10.10±0.15(Predicted)

    Critical Temperature & Pressure:

    2-8°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

    Location:

    National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5 days

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2014

    Company Certificates
    • LEADER BIOCHEMICAL GROUPLevel A of Tax Credit Registration Assessment by Government Level A of Tax Credit Registration Assessment by Government
    • LEADER BIOCHEMICAL GROUPGood Product Quality Management Certificate of Shanxi Province,China Good Product Quality Management Certificate of Shanxi Province,China
    • LEADER BIOCHEMICAL GROUPCompany Trade Union Qualification Certificate Company Trade Union Qualification Certificate
    • LEADER BIOCHEMICAL GROUPExcellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina
    • LEADER BIOCHEMICAL GROUPAAA TOP Credit Excellent Group Enterprise of Shanxi Province,China AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China
    • LEADER BIOCHEMICAL GROUPFDA FDA


    24 Hours Team Service

    Email

    info@leader-biogroup.com   

    Hot Line

    +86-029-68895030  

    +86-029-68569961  

    +86-029-68569962  

    Fax

    +86-029-68895030


    Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories Base with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world.

    • Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.

      Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.

      Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.

      We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

    • Process Capability :   It has more than 100 sets of multi-functional reaction reactors, such as 100l~6300l enamel, stainless steel, Hastelloy, etc. It can realize Grignard, coupling, bromination, Wittig reaction and other conventional reactions. There are microchannel reactor workshops, which can realize continuous production, energy conservation and emission reduction. It can realize high pressure, high vacuum rectification, ultra-low temperature (-80 ℃ ~-100 ℃), ultra-high temperature (300 ℃ ~400 ℃) and other special reactions. It can realize the customization and processing of customers' products.

                                      

        Factory Overview

                                                                                 Factory Production Lines

    Our Professional Lab

                               Factory Warehouse 

    Factory Logistics Departments

    GROUP HONOR

    Honor Name: Level A of Tax Credit Registration Assessment   
    Issued By:National Administration of Taxation & Shaanxi Tax Bureau   
    Authorised Date:2018-09-16  
    Description: National Administration of Taxation & Shaanxi Tax Bureau




    Honor Name: AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China  
    Issued By:China Association of Shaanxi product Quality management Center   
    Authorised Date:2018-12-31  
    Description:AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China



    Honor Name:Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina

    Issued By: China Association of Shaanxi product Quality management Center

    Authorised Date:2018-12-31

    Description: Excellent Group Enterprise of Quality and Integrity in Shaanxi Province,China



    Honor Name: Products Patent Certificates


  • Inquiry History
    38 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Alpha-arbutin

    10.00 MT Dec 13, 2023
    India

    Alpha-arbutin

    100.00 KG Jan 25, 2024
    India

    Alpha-arbutin

    10.00 MT Dec 15, 2023
    India

    Alpha-arbutin

    5.00 KG Jan 19, 2024
    India

    Alpha-arbutin

    1.00 MT Jan 24, 2024
    India

    Alpha-arbutin

    1.00 MT Jan 3, 2024
    India

    Alpha-arbutin

    20.00 MT Dec 11, 2023
    Pakistan

    Alpha arbutin

    1000.00 KG Oct 11, 2025
    Pakistan

    Alpha Arbutin

    1000.00 KG Mar 25, 2025
    United Arab Emirates

    Alpha-arbutin

    1.00 TON Mar 6, 2025
    India

    Alpha-arbutin

    1.00 MT Sep 10, 2024
    India

    Alpha arbutin

    50.00 KG Jul 4, 2024
    India

    Alpha-arbutin

    100.00 KG Dec 14, 2023
    Saudi Arabia

    Alpha Arbutin

    1 KG Jun 26, 2026
    Bangladesh

    Alpha Arbutin

    20.00 KG Mar 5, 2026
    Pakistan

    Alpha arbutin

    1000.00 KG Aug 6, 2025
    Egypt

    alpha arbutin

    1000.00 KG Jul 4, 2025
    Egypt

    Alpha arbution

    200.00 KG May 20, 2025
    India

    Alpha-arbutin

    50.00 KG Jun 24, 2024
    India

    Alpha arbutin

    100 KG Dec 29, 2023
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