Notoginsenoside R1
80418-24-2
Industrial Grade
99%
CUIKANG
G/bottle; Kg/bag; 25kg/barrel
2025-01-30
Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceNotoginsenoside R1, the main bioactive component in panaxnotoginseng, is reported to have some neuronal protective, antihypertensive effects. IC50 value:Target:In vitro:In vivo: Notoginsenoside R1 significantly reduce blood pressure in spontaneously hypertensive rats and induce nitric oxide generation through increasing the phosphorylation of iNOS. Notoginsenoside R1 reduces the caudal blood pressure of spontaneously hypertensive rats through induction of iNOS regulated by long non-codin
Notoginsenoside R1 is a ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an apoptosis inducer and a phytoestrogen. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a disaccharide derivative, a ginsenoside, a tetracyclic triterpenoid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.Basic Info-
Product Name:
Notoginsenoside R1
Other Name:β-D-Glucopyranoside,(3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-;Dammarane,β-D-glucopyranoside deriv.;(3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside;Notoginsenoside R1;Sanchinoside R1;Sanqi glucoside R1
CAS No.:80418-24-2
Molecular Formula:C47H80O18
InChIKeys:InChIKey=LLPWNQMSUYAGQI-OOSPGMBYSA-N
Molecular Weight:933.13
Exact Mass:933.13
UNII:Z62692362Z
Color/Form:White to off-white powder
HScode:29389090
Categories:
Characteristics-
PSA:
298
XLogP3:log Kow = -0.66 (est)
Appearance:white to off-white
Density:1.4±0.1 g/cm3
Melting Point:215～217℃
Boiling Point:1010.5°C at 760 mmHg
Flash Point:564.9±34.3 °C
Refractive Index:1.614
Water Solubility:H2O: soluble1mg/mL, clear, colorless
Storage Conditions:2-8°C
Vapor Pressure:6.7X10-38 mm Hg at 25 °C (est)
Henrys Law Constant:Henry's Law constant = 1.5X10-31 atm-cu m/mol at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials
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Location:
D307, Zhuque Square Office Building, No. 14, Chang'an North Road, Beilin District, Xi'an City, Shaanxi Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
45
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Certifications:
ISO,ISO,ISO
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