Nelarabine Manufacturer/High quality/Best price/In stock
121032-29-9
according to the clients requirement
2024-12-31
N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol
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Product Description
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Seller Information
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DescriptionKeywords
Competitive price/ Top quality of Nelarabine
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Quick DetailsProName:Nelarabine Manufacturer/High quality/Best price/In stock
CasNo:121032-29-9
Molecular Formula:C11H15N5O5
Appearance:detailed see specifications
Application:It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
DeliveryTime:prompt
PackAge:according to the clients requirement
Port:Shanghai
ProductionCapacity:1-100 Metric Ton/Month
Purity:98%
Storage:Store in dry, dark and ventilated place.
Transportation:by sea or by air
LimitNum:1 Kilogram
SuperiorityDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities of custom synthesis chemicals in lab, plant and industrial scale with more than fifteen years.
Pls contact with us freely for getting detailed product specifications, product tech. date sheet, COA and MSDS, prices, delivery time and payment terms.
DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product's supplier in China, Dayangchem is your best choice.
Details
Dayang Chem (Hangzhou) Co.Limited, established in 2000, dedicated to the development, production and marketing of chemicals. We are a leading manufacturer and supplier of chemicals in China.
Manufacturing base: The Company has some Manufacturing base in Zhejiang, Jiangsu and Shandong provide. These bases focus on production and Contract Manufacturing.
Strong quality control system: Strength of our ethical commitment to quality control and quality assurance systems firmly based on ISO standard. QA and QC used in the whole process of raw material control, process control and finished product quality inspection.
Sales agent: Dayangchem are authorized by many Chinese chemical manufacturers as universal agency and international area agency. Dayangchem has established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long time business intercourse.
Rich experience in sales: 1000 square meters of office space with independent property rights, Sales team of nearly 40 people. Our customers throughout the world, especially the world-renowned companies, such as BACHEM, BASF, CELANESE, CORDEN,DOW,EVONIK, GENZYME,HENKEL, MERCK,ROCHE,SANOFI,SOLVAY.
Flexible payment terms: Various payment terms such as L/C,D/P,D/A and T/T will be accepted. Special Notice: DAYANGCHEM never require customers to remit payment to a personal account. Beware of being cheated.
ECHEMI Editorial ReferenceChEBI: A purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N9-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta /stereo >-D-arabinofuranosylguanine (ara-G).Nelarabine is a new member of the purine nucleoside antimetabolite class of drugs. It was launched as an intravenous infusion for treating relapsed or refractory T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) after at least two prio
Solid
Nelarabine is a purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G). It has a role as an antineoplastic agent, a DNA synthesis inhibitor and a prodrug. It is a purine nucleoside, a beta-D-arabinoside and a monosaccharide derivative. It derives from a guanine and a 9-beta-D-arabinofuranosylguanine.|Nelarabine is an antineoplastic agent that is typically employed to treat acute T-cell lymphoblastic leukemia. Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity.|Nelarabine is a Nucleoside Metabolic Inhibitor. The mechanism of action of nelarabine is as a Nucleic Acid Synthesis Inhibitor.|Nelarabine is a purine analogue and antineoplastic agent used in the therapy of T cell lymphoblastic leukemia or lymphoma. Nelarabine is associated with a low rate of transient serum enzyme elevations during therapy and has been linked to rare instances of clinically apparent acute liver injury with jaundice.|Nelarabine is an arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9-beta-D-arabinosylguanine (ara-G); ara-G incorporates into DNA, thereby inhibiting DNA synthesis and inducing an S phase-dependent apoptosis of tumor cells. (NCI04)Basic Info-
Product Name:
Nelarabine
Other Name:9H-Purin-2-amine,9-β-D-arabinofuranosyl-6-methoxy-;9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine;506u;Nelzarabine;MAY;GW 506U78;Nelarabine;Arranon;Atriance
CAS No.:121032-29-9
Molecular Formula:C11H15N5O5
InChIKeys:InChIKey=IXOXBSCIXZEQEQ-UHTZMRCNSA-N
Molecular Weight:297.27
Exact Mass:297.27
EC Number:1806241-263-5
UNII:60158CV180
NSC Number:755985
DSSTox ID:DTXSID6046842
NCI Thesaurus Code:C1704
ATC Code:L01BB07|L - Antineoplastic and immunomodulating agents
Categories:
Characteristics-
PSA:
149
XLogP3:-0.7
Density:1.98±0.1 g/cm3(Predicted)
Melting Point:208-210 °C @ Solvent: Methanol
Boiling Point:721.0±70.0 °C(Predicted)
Flash Point:389.9±35.7 °C
Refractive Index:1.829
Water Solubility:Slightly soluble to soluble in water
Specific rotation:D20 +55.9° (c = 0.27 in DMF)
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 2
Carcinogenicity, Category 2
Reproductive toxicity, Category 2
Specific target organ toxicity â repeated exposure, Category 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H341 Suspected of causing genetic defects
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
H413 May cause long lasting harmful effects to aquatic life
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
Response P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol
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Location:
RM901-7,Unit 2,259# WenSan Road, Xihu District, Hangzhou Zhejiang, China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
2
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2020
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Certifications:
Dangerous Chemicals Business License,Pesticide Business License,ISO 9001:2015
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
