Adefovir
106941-25-7
Industrial Grade
according to the clients requirement
Yes
2024-12-31
N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol
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Product Description
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Seller Information
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DescriptionKeywords
Adefovir Manufacturer in China
Adefovir High quality low price in stock
Adefovir Supplier in China
Quick DetailsProName:Adefovir
CasNo:106941-25-7
Molecular Formula:C8H12N5O4P
Appearance:Detailed see specifications
Application:It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
DeliveryTime:prompt
PackAge:according to the clients requirement
Port:Shanghai
ProductionCapacity:1-10 Metric Ton/Month
Purity:98%
Storage:Store in dry, dark and ventilated place.
Transportation:by sea or by air
LimitNum:1 Kilogram
Grade:Industrial Grade
SuperiorityAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis chemicals in lab, plant and industrial scale with more than fifteen years.
DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice.
Pls contact with us freely for getting detailed product specifications, product tech. date sheet, COA and MSDS, prices, delivery time and payment terms.
DetailsDayang Chem (Hangzhou) Co. Limited, established in 2000, dedicated to the development, production and marketing of chemicals. We are a leading manufacturer and supplier of chemicals in China.
Manufacturing base: The Company has some Manufacturing base in Zhejiang, Jiangsu and Shandong provide. These bases focus on production and Contract Manufacturing.
Sales agent: Dayangchem are authorized by many Chinese chemical manufacturers as universal agency and international area agency. Dayangchem has established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long time business intercourse.
Strong quality control system: Strength of our ethical commitment to quality control and quality assurance systems firmly based on ISO standard. QA and QC used in the whole process of raw material control, process control and finished product quality inspection.
Third lab test: Audit directly and tested by third party like SGS or INTERTEK in any time will be accepted under required.
Flexible payment terms: Various payment terms such as L/C,D/P,D/A and T/T will be accepted. Special Notice: DAYANGCHEM never require customers to remit payment to a personal account. Beware of being cheated.
Rich experience in sales: 1000 square meters of office space with independent property rights, Sales team of nearly 40 people. Our customers throughout the world, especially the world-renowned companies, such as BACHEM, BASF, CELANESE, CORDEN,DOW,EVONIK, GENZYME,HENKEL, MERCK,ROCHE,SANOFI,SOLVAY.
ECHEMI Editorial ReferenceAdefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses[1][2][3].
Adefovir is a member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens has been replaced by a 2-(6-amino-9H-purin-9-yl)ethoxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(t-butoxycarbonyloxymethyl) ester (dipivoxil ester) prodrug is used to treat chronic hepatitis B viral infection. It has a role as a HIV-1 reverse transcriptase inhibitor, a drug metabolite, an antiviral drug, a nephrotoxic agent and a DNA synthesis inhibitor. It is a member of 6-aminopurines, an ether and a member of phosphonic acids. It derives from an adenine. It is a conjugate acid of an adefovir(1-).|Adefovir is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of adefovir is as a Nucleoside Reverse Transcriptase Inhibitor.|Adefovir dipivoxil is an acyclic nucleotide analogue of adenosine used either alone or in combination with other agents as therapy of chronic hepatitis B. Adefovir does not appear to be a significant cause of drug induced liver injury, but initiation of therapy and sudden withdrawal of therapy can induce a transient exacerbation of the underlying hepatitis B.|Adefovir is a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV).Basic Info-
Product Name:
Adefovir
Other Name:Phosphonic acid,P-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-;Phosphonic acid,[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-;P-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid;9-(2-Phosphonylmethoxyethyl)adenine;PMEA;9-[2-(Phosphonomethoxy)ethyl]adenine;GS 0393;Adefovir;((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonicacid;[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid;2-(6-Aminopurin-9-yl)ethoxymethylphosphonic acid
CAS No.:106941-25-7
Molecular Formula:C8H12N5O4P
InChIKeys:InChIKey=SUPKOOSCJHTBAH-UHFFFAOYSA-N
Molecular Weight:273.19
Exact Mass:273.19
EC Number:1806241-263-5
UNII:6GQP90I798
DSSTox ID:DTXSID6046214
NCI Thesaurus Code:C61526
Color/Form:Off-white crystalline solid
HScode:2933990090
Categories:
Characteristics-
PSA:
136
XLogP3:-2
Appearance:white to beige
Density:1.88
Melting Point:301 °C
Boiling Point:632.5ºCat 760 mmHg
Flash Point:336.3±34.3 °C
Refractive Index:1.769
Water Solubility:0.1 M NaOH: ≥5mg/mL
Storage Conditions:-20°C Freezer
Vapor Pressure:6.06X10-11 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 3.85X10-24 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa1 = 2.0; pKa2 = 6.8|pKa1 = 2.42 (hydroxyl); pKa2 = 3.65 (benzylimine); pKa3 = 7.17 (hydroxyl) (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol
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Location:
RM901-7,Unit 2,259# WenSan Road, Xihu District, Hangzhou Zhejiang, China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
2 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2020
Company Certificates-
Dangerous Chemicals Business License
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Pesticide Business License
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ISO 9001:2015
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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