China Most Professional Factory Supply High Qulity Fazarabine CAS 65886-71-7
GMP HALAL KOSHER ISO FDA TDS
65886-71-7
Pharmaceutical Grade
99%
Shanghai
Leader
25KG/Drum
2024-01-09
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceFazarabine is an N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-arabinofuranosyl residue via an N-glycosidic linkage. A synthetic analogue of cytosine arabinoside and 5-azacytidine that incorporates structural features of both compounds, it shows good activity against a variety of transplanted tumors. It has a role as an antineoplastic agent. It is a N-glycosyl-1,3,5-triazine and a nucleoside analogue. It derives from a beta-D-arabinofuranose.|Fazarabine is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. (NCI04)Certificates
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TDS
Basic Info-
Product Name:
Fazarabine
Other Name:1,3,5-Triazin-2(1H)-one,4-amino-1-β-D-arabinofuranosyl-;4-Amino-1-β-D-arabinofuranosyl-1,3,5-triazin-2(1H)-one;1-β-D-Arabinofuranosyl-5-azacytosine;5-Azacytosine arabinoside;NSC 281272;Fazarabine;ara-AC;5-Aza-1-arabinosylcytosine;Kymarabine
CAS No.:65886-71-7
Molecular Formula:C8H12N4O5
InChIKeys:InChIKey=NMUSYJAQQFHJEW-ARQDHWQXSA-N
Molecular Weight:244.20
Exact Mass:244.20
UNII:5V71D8JOKK
NCI Thesaurus Code:C1096
Categories:
Characteristics-
Melting Point:
220 °C (decomp)
Water Solubility:Water > 16 (mg/mL)|Ethanol insoluble (mg/mL)|Dimethylsulfoxide > 165 (mg/mL)
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Seller Information
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Business Type:
Manufactory
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Main Products:
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients
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Location:
National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
5
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
Above 1000
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Year of Establishment:
2014
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Certifications:
Level A of Tax Credit Registration Assessment by Government,Good Product Quality Management Certificate of Shanxi Province,China,Company Trade Union Qualification Certificate,Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina,AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China,FDA
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