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Ceritinib  1032900-25-6 buy - large image1
Ceritinib  1032900-25-6 buy - image1

Ceritinib 1032900-25-6

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

1032900-25-6

Port:

shanghai

Packaging:

as request

Price valid (until):

2023-09-12

Company Type:
Trader
Location:
China
Qualification:
Main Products:

13-Dimethyladamantane,1-Bromo-35-dimethyladamantane,perhydroacenaphthylene,4-[1,1-bis(4-hydroxyphenyl)ethyl]phenol,CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER, TRANS

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    Ceritinib


    CAS number 1032900-25-6
    Molecular weight 558.135
    Density 1.3± 0.1g /cm3
    Boiling point 720.7±70.0 °C at 760 mmHg
    Molecular formula C28H36ClN5O3S
    Flash point 389.6±35.7 °C




    Ceritinib (INN, trade name Zykadia) is a drug for the treatment of a specific type of lung cancer. It is an anaplastic lymphoma kinase (ALK) inhibitor. It was developed by Novartis. It was approved in April 2014 by the Food and Drug Administration for the treatment of ALK-positive metastatic non-small cell lung cancer (NSCLC) in patients that failed treatment with crizotinib. It is a more effective, but more toxic, alternative to traditional platinum-based chemotherapies. Ceritinib was found at physiological concentrations to inhibit ALK, insulin-like growth factor 1 receptor (IGF-1R), and ROS1.

    Basic Info
    Product Name:

    Ceritinib

    Other Name:

    2,4-Pyrimidinediamine,5-chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-;5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine;LDK 378;Ceritinib;Zykadia;1431456-10-8

    CAS No.:

    1032900-25-6

    Molecular Formula:

    C28H36ClN5O3S

    InChIKeys:

    InChIKey=VERWOWGGCGHDQE-UHFFFAOYSA-N

    Molecular Weight:

    558.13514

    Exact Mass:

    558.14

    EC Number:

    -0

    Categories:

    Antineoplastic Agents

    Characteristics
    PSA:

    114

    XLogP3:

    6.4

    Density:

    1.251±0.06 g/cm3(Predicted)

    Boiling Point:

    720.7±70.0 °C(Predicted)

    Flash Point:

    389.6±35.7 °C

    Refractive Index:

    1.595

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    13-Dimethyladamantane,1-Bromo-35-dimethyladamantane,perhydroacenaphthylene,4-[1,1-bis(4-hydroxyphenyl)ethyl]phenol,CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER, TRANS

    Location:

    Room 1623,Building A, ZhongqiaoCenter,Goverment District,Hefei city,Anhui Province,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2019

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Ceritinib

    10 KG Dec 19, 2023
    Germany

    ceritinib

    40 KG Apr 30, 2024
    Post an enquiry for this product
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