Product Overview

Epithalon (also known as Epitalon, Epithalone, or AEDG peptide) is a synthetic tetrapeptide composed of four amino acids: Alanine (Ala), Glutamic Acid (Glu), Aspartic Acid (Asp), and Glycine (Gly) – hence the sequence AEDG . It is a synthetic analog of Epithalamin, a crude polypeptide complex originally extracted from the bovine pineal gland .

The peptide was developed in the 1980s by a research team led by Professor Vladimir Khavinson of the St. Petersburg Institute of Bioregulation and Gerontology and has since been the subject of extensive research in cell cultures, animals, and humans . Over the past 25 years, Epithalon has been extensively studied for its geroprotective, antioxidant, and neuroendocrine properties .

Our Epithalon is supplied as a high-purity lyophilized powder, manufactured under strict quality control standards, suitable for research and biochemical applications only.

Research Applications

Epithalon has been investigated across multiple research domains:

1. Anti-Aging & Longevity Research

• Telomere elongation and telomerase activity studies

• Age-associated disease progression research

• Cellular senescence and lifespan extension models

2. Neuroendocrine Research

• Melatonin synthesis and circadian rhythm regulation

• Gonadotropic hormone (FSH, LH, prolactin) modulation

• Sleep cycle and pineal gland function studies 

3. Oncology Research

• Inhibition of spontaneous tumor development in research models 

• Anti-tumor effects in breast and colorectal cancer research 

• Carcinogenic receptor expression inhibition

4. Inflammation & Immunology

• Cytokine and C-reactive protein regulation

• Research on rheumatoid arthritis and ulcerative colitis models 

• Thymocyte mitogenic activity modulation 

5. Neuroprotection & Wound Healing

• Neuronal activity enhancement (intranasal administration models) 

• Wound healing in diabetic retinopathy models

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