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DL-Alpha Tocopheryl Acetate, CAS No.: 52225-20-4 buy - large image1
DL-Alpha Tocopheryl Acetate, CAS No.: 52225-20-4 buy - image1

DL-Alpha Tocopheryl Acetate, CAS No.: 52225-20-4

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CAS No.:

52225-20-4

Grade:

Food Grade

Content:

96.5%

Port:

Shanghai or Beijing

Brand:

HANDOM CHEM

Packaging:

20kg/Drum or according to the specific requirements from customers

Price valid (until):

2024-02-28

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Details  


    Product Name: DL-Alpha Tocopheryl Acetate

    Alias: DL-Alpha-Tocopheryl Acetate;DL-Alpha-Tocopherol Acetate; DL-α-Tocopherol acetate; DL-α-Tocopheryl acetate; Vitamin E acetate; vitamin E derivative; Synthesis VE acetate; Synthesis Vitamin E Acetate

    CAS No.: 52225-20-4

    EINECS No.: 257-757-7

    Molecular Formula: C31H52O3

    Molecular Weight: 472.75

    Brief Introduction:

    DL-Alpha-Tocopheryl Acetate is the general name of tocopherol (T) and tocotrienol (T-3), and is a fat-soluble vitamin. An important component of the cell membrane. It is also the main antioxidant in cell membranes. DL-α-tocopheryl acetate is widely found in animal and plant foods: Animal foods are mainly da-type; Vegetable oils have a higher content of DL-α-tocopherol acetate, which is parallel to the content of polyene fatty acids such as linoleic acid.


    DL-α-Tocopheryl acetate is an antioxidant of polyene fatty acids. It combines with the pol-yunsaturated fatty acid(PUFA) of membrane phospholipids on the cell membrane to form a complex to stabilize the membrane structure, preventing PUFA on biofilms and sulfur-containing enzymes in cells from being damaged by oxidants. When DL-α-tocopherol acetate is deficient, the PUFA on the red blood cell membrane is prone to peroxidation, causing damage to the red blood cell membrane and causing hemolysis.

    Character:

    DL-Alpha Tocopheryl Acetate is a slightly yellow to yellow or yellow-green clear viscous liquid; almost odorless; its color gradually turns darker when exposed to light. The natural type will solidify when placed and melts at around 25°C. This product is easily soluble in absolute ethanol, acetone, ether or vegetable oil, but insoluble in water.

    Test Items
    Test Methods Specifications
    Description Visual Clear, colourless slightly greenish-yellow, Viscous, oily liquid, Ph.Eur./USP/FCC



    Identification

    Optical Rotation Ph.Eur.2.2.7 -0.01°~ +0.01°, Ph.Eur.
    IR Ph.Eur.2.2.24 To conform, Ph.Eur./USP/FCC
    Colour Reaction USP To conform, USP/FCC
    Retention Time GC To conform, USP/FCC




    Related Substances



    Impurity A Ph.Eur.2.2.28 Not more than 0.5%
    Impurity B Ph.Eur.2.2.28 Not more than 1.5%
    Impurity C Ph.Eur.2.2.28 Not more than 0.5%
    Impurities D and E Ph.Eur.2.2.28 Not more than 1.0%
    Any other impurity Ph.Eur.2.2.28 Not more than 0.25%
    Total impurities Ph.Eur.2.2.28 Not more than 2.5%
    Acidity USP/FCC Not more than 1.0mL
    Residual Solvents Ph.Eur.2.4.24 USP<467> To conform (In-house)




    Heavy Metals

    Lead (Pb) AA Not more than 2 mg/kg, FCC
    Arsenic (As) ChP0822 Not more than 1 mg/kg (In-house)
    Copper (Cu) ICP-MS Not more than 25 mg/kg (In-house)
    Zinc (Zn) ICP-MS Not more than 25 mg/kg (In-house)
    Palladium (Pd) AA Not more than 5 mg/kg (In-house)
    Assay (Ph.Eur.) Ph.Eur.2.2.28 96.5% ~ 102.0%, Ph. Eur.
    Assay (Ph.Eur.) Ph.Eur.2.2.28 434.3mg α-tocopherol/g ~ 459.0mg α-tocopherol/g, Ph.Eur.
    Assay (USP/FCC) Ph.Eur.2.2.28 96.0% ~ 102.0%, USP/FCC
    Assay (USP/FCC) Ph.Eur.2.2.28 432.0mg α-tocopherol/g ~ 459.0mg α-tocopherol/g, USP/FCC





    Microbial Limit Test

    Total aerobic microbial count USP<61> Ph.Eur.2.6.12 Not more than 1000 CFU/g
    Total yeast and mould count USP<61> Ph.Eur.2.6.12 Not more than 100 CFU/g
    Escherichia coli USP<62> Ph.Eur.2.6.13 Negative/g
    Pseudomonas aeruginosa USP<62> Ph.Eur.2.6.13 Negative/g
    Staphylococcus aureus USP<62> Ph.Eur.2.6.13 Negative/g
    Enterobacterial USP<62> Ph.Eur.2.6.13 Negative/g
    Salmonella USP<62> Ph.Eur.2.6.13 Negative/10g

    Test Standard:

    Ph.Eur./USP/FCC

    Pharmacological Effects:

    DL-alpha-tocopherol acetate is an essential nutrient whose exact function is unknown and is an antioxidant. It can combine with selenium in the diet to protect cell membranes and other cell structures from polyvalent unsaturated fatty acids from free radical damage, protect red blood cells from hemolysis, and protect nerves and muscles from oxygen free radical damage, maintains the normal development and function of nerves and muscles, and may also be a cofactor for certain enzyme systems.


    It affects reproductive function, lipid metabolism, etc. It can cause hyperactivity of adenohypophysis gonadotrophic secretory cells, increase secretion, and promote sperm production and activity, increase ovarian function, increase follicles, luteal cells and enhance the effect of progesterone; Deficiency can cause damage to the animal's reproductive organs, making it difficult for fertilization or causing habitual abortion. It can also improve lipid metabolism. When lacking, it can increase the levels of cholesterol and triacylglycerol in animals, leading to atherosclerosis.


    Large doses of DL-α-tocopherol acetate can promote the proliferation of capillaries and small blood vessels and improve peripheral circulation. It has also been reported that it can improve metabolic abnormalities in diabetes.

    Indications:

    Supportive care for some conditions includes various types of cataracts, diabetic retinopathy, optic atrophy, viral keratitis, ophthalmoplegia, various types of chorioretinopathy, retrolental fibroplasia, primary retinitis pigmentosa, macular degeneration, corneal degeneration and malignant exophthalmos, etc.


    Also used for coronary atherosclerotic heart disease (coronary heart disease) and lipid metabolism disorders; also used for anti-aging.

    Packaging:

    20kg/Drum or according to the specific requirements from customers.

    Storage Conditions:

    Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

    Shelf Life:

    36 months if stored under above mentioned conditions.

    Certificates

    Basic Info
    Product Name:

    DL-α-Tocopherol acetate

    Other Name:

    2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,6-acetate,(2R)-rel-;2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-,acetate,[2R*(4R*,8R*)]-(±)-;2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,acetate,(2R)-rel-;DL-α-Tocopherol acetate;DL-α-Tocopheryl acetate;Ephynal;Syntopherol acetate;dl-α-Tocopherol acetate;dl-α-Tocopheryl acetate;(±)-α-Tocopherol acetate;all-rac-α-Tocopheryl acetate;Rovimix E 50SD;Toco500;E-Vimin;OptoVit E;dl-Vitamin E acetate;Vitagutt;Eusovit;Detulin;Rovimix E 50AS;SynAC;Rovimix E 50Ads;Evigen;Alfacol;Fertilvit;Gevex;α-Tocopherol acetate;α-Tocopheryl acetate;Tocopherol acetate;Diluvac Forte;Rovimix E 50;Rovimix E;Dry Vitamin E 50% CWS/A;18920-61-1;54-22-8;133-80-2;1407-18-7

    CAS No.:

    52225-20-4

    Molecular Formula:

    C31H52O3

    InChIKeys:

    InChIKey=ZAKOWWREFLAJOT-XVJJFFMLNA-N

    Molecular Weight:

    472.74300

    Exact Mass:

    472.74

    Characteristics
    PSA:

    35.53000

    XLogP3:

    9.05990

    Density:

    0.96g/mL

    Melting Point:

    -27.5 °C

    Boiling Point:

    184 °C @ Press: 0.01 Torr

    Flash Point:

    235.6ºC

    Refractive Index:

    n20/D 1.497

    Storage Conditions:

    2-8ºC

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

    Location:

    RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Egypt

    Vitamin E oil

    200.00 KG Sep 14, 2023
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