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Unii-bzf2zm0I5z

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CAS No.:

857402-23-4

Grade:

Industrial Grade

Content:

98%

Port:

shanghai

Packaging:

G/bottle,Kg/bag,25kg/barrel

Price valid (until):

2024-02-29

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Shaanxi Cuikang Pharmaceutical Technolog

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

45 days

Qualification:

Main Products:

Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials

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Product Description
Seller Information

Description
Product Detail

Retamycin is an antibiotic used to treat symptoms of various infections, such as respiratory tract infections, skin and soft tissue infections, urinary tract infections, peritonitis, and septicemia. Retamycin blocks the synthesis of peptidoglycan in bacteria, causing the bacterial cell wall to become weak and eventually lysis and death. In addition, retamycin has also been found to inhibit the growth of tumor cells and is a potential cancer treatment. However, retamycin also has certain side effects, such as hepatotoxicity, nephrotoxicity, ototoxicity, etc., so it needs to be used with caution

Items Specifications

ECHEMI Editorial Reference

Retaspimycin is an ansamycin that is tanespimycin in which the benzoquinone moiety has been reduced to the corresponding hydroquinone. A semi-synthetic analogue of geldanamycin, it is used (generally as the hydrochloride salt) in cancer treatment. It has a role as a Hsp90 inhibitor and an antineoplastic agent. It is a member of hydroquinones, an ansamycin, an organic heterobicyclic compound, a secondary amino compound, a semisynthetic derivative and a carbamate ester. It derives from a geldanamycin. It is a conjugate base of a retaspimycin(1+).|Retaspimycin is a small-molecule inhibitor of heat shock protein 90 (HSP90) with antiproliferative and antineoplastic activities. Retaspimycin binds to and inhibits the cytosolic chaperone functions of HSP90, which maintains the stability and functional shape of many oncogenic signaling proteins and may be overexpressed or overactive in tumor cells. Retaspimycin-mediated inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins in susceptible tumor cell populations, which may result in the induction of apoptosis.
Research & Reference Note

Unii-bzf2zm0I5z is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Authoritative sources

PubChem

ClinicalTrials.gov

FDA Drugs@FDA

NIH
Disclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals
Basic Info

Product Name:
Retaspimycin

Other Name:
Geldanamycin,18,21-didehydro-17-demethoxy-18,21-dideoxo-18,21-dihydroxy-17-(2-propen-1-ylamino)-;Geldanamycin,18,21-didehydro-17-demethoxy-18,21-dideoxo-18,21-dihydroxy-17-(2-propenylamino)-;18,21-Didehydro-17-demethoxy-18,21-dideoxo-18,21-dihydroxy-17-(2-propen-1-ylamino)geldanamycin;17 AAGH2;Retaspimycin

CAS No.:
857402-23-4

Molecular Formula:
C31H45N3O8

InChIKeys:
InChIKey=OAKGNIRUXAZDQF-TXHRRWQRSA-N

Molecular Weight:
587.7

Exact Mass:
587.70

UNII:
BZF2ZM0I5Z

NCI Thesaurus Code:
C80378

Categories:
Bulk Drug Intermediates
Seller Information

Business Type:
Manufactory

Main Products:
Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials

Location:
D307, Zhuque Square Office Building, No. 14, Chang'an North Road, Beilin District, Xi'an City, Shaanxi Province

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
45 days

Total Annual Revenue:
Less than $1 million

Total Employees:
11-50

Year of Establishment:
2023

Company Certificates
- ISO
- ISO
- ISO
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd., founded in January 2023, is a wholly-owned subsidiary of Shaanxi Cuicheng Bio-pharmaceutical Technology Co., Ltd., and a comprehensive innovative enterprise focusing on the research and development, production, sales, import and export trade, technical services and related resource allocation and integration of products in the field of fine chemistry and biochemistry. The company has built a 2700 square meter R&D center in Hanzhong, Shaanxi Province, and has established in-depth and stable cooperative relations with three factories, which can provide one-stop service for domestic and foreign customers from pilot R&D to industrial scale-up production.

Cuikang Company is an enterprise integrating natural products, fine chemicals, biological fermentation, innovative material research and development, production, sales and technical services. It can provide global customers with a series of products with different specifications and models, such as proportional plant extracts, content plant extracts, synthetic chemical blocks, synthetic pharmaceutical intermediates, active API molecules, fermented pharmaceutical intermediates and APIs, health food, functional food raw materials, veterinary drug raw materials, pharmaceutical innovative materials, laboratory equipment, pharmaceutical machinery and equipment.

The company adheres to the market demand-oriented, technical innovation as the starting point, product quality as the core, customer service as the foundation, and the enterprise spirit of "professional integrity", and wholeheartedly provides high-quality products and services for customers at home and abroad.
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