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152-62-5 | ChemExpress buy - large image1
152-62-5 | ChemExpress buy - image1

152-62-5 | ChemExpress

10 Inquiries

Unit Price: Get Latest Price
CAS No.:

152-62-5

Port:

shanghai

Packaging:

10 kg

Price valid (until):

2024-04-01

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

CRO

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Dydrogesterone

    API of Dydrogesterone for the treatment of the prevention of threatened and habitual miscarriages
    We can provide high-quality Dydrogesterone and its derived impurities.


    Brand:ChemExpress
    CAS:152-62-5
    Catalog_No:HY-B0257A
    Molecular Formular:C21H28O2
    Molecular Weight:312.45


    Contact:
    TEL:+1-970-439-2030 (USA)、+86 (21) 5895-0125 (Global)
    Email:info@chemexpress.com



    Brand Introduction:
    ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.


    ChemExpress Services:
     
    Drug Discovery: synthetic chemistry; medicine chemistry; FTE/FFS services.

    Process Development: APIs and intermediates development; formulation development.

    New Modalities Development: ADC; peptide; oligonucleotide and so on.

    Manufactory: support production from milligrams to kilograms, both with GMP and non-GMP capabilities.

    Analytical Development & Quality Control: R&D testing; stability study; genotoxic impurity research and so on.

    Regulatory CMC Support

    Eany development services in Synthetic Chemistny:Providing serices related to high qualty compound synthesis,chemical custom synthesis and analytical chemistry.

    Pharmaceutical Chemistry eaniy development services: including high-throughput screening, drug synthesis, seding compounds, lead compounds, and IND fling support.

    Process development: Covers AP! & intermediates process development, validation, transfer, and formulation development.

    Commerial producion:it hasa research and development base forthe producion otapis intermediates and prenarations and provdes commeria prouction semices.

    CMC services: Provide one-stop CMC services, from lND to NDA stage of pharmaceutical research and development and dedlaration services, accelerate IND declaration.

    ADC drug and highly active drug development and production:  Provides a one-stop CRO & CDMO service for the small molecule aspect of ADC drugs, as well as customized ADC conjugation services. 

    Oligonucleotide drug process development and production: Provide oligonucleotide customized products and services to meet different needs.

    Analytical testing services and quality control: Provide integrated analytical testing services and drug quality research support

    ChemExpress committed to being a steadfast companion for our clients, gaining profound insight into their needs. Our focus is on accelerating the empowerment of global partners across the full spectrum, from preclinical stages to commercial production. This commitment aims for more streamlined drug development, swifter market entry, and an earlier positive impact on human health.


    Product details:https://www.chemexpress.com/product/HY-B0257A

    ECHEMI Editorial Reference
    Figure 1 the chemical structure of dydrogesterone ; Dydrogesterone is a stereoisomer of progesterone with an additional double bond between C6 and C7, and its hormonal pattern and metabolism differ largely from those of the natural progestogen. It is an orally active progestin that is non-thermogenetic, non-sedative and does not inhibit gonadotropin release and ovulation. It has weak antimineralocorticoid effects, negligible androgenic and glucocorticoid activities, and no antiandrogenic pro
    Solid
    Dydrogesterone is a 3-oxo-Delta(4) steroid and a 20-oxo steroid. It has a role as a progestin.|A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.|A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit OVULATION.

    Basic Info
    Product Name:

    Dydrogesterone

    Other Name:

    Pregna-4,6-diene-3,20-dione,(9β,10α)-;9β,10α-Pregna-4,6-diene-3,20-dione;(9β,10α)-Pregna-4,6-diene-3,20-dione;6-Dehydro-9β,10α-progesterone;6α-Dehydro-retro-Δ4-pregnene-3,20-dione;6-Dehydroretroprogesterone;Diphaston;Dydrogesterone;Hydrogesterone;Retro-6-dehydroprogesterone;Retroprogesterone,6-dehydro-;Terolut;Isopregnenone;Δ6-Retroprogesterone;Duphaston;Gestatron;Prodel;Retrone;Dufaston;Duvaron;Gynorest;NSC 92336

    CAS No.:

    152-62-5

    Molecular Formula:

    C21H28O2

    InChIKeys:

    InChIKey=JGMOKGBVKVMRFX-HQZYFCCVSA-N

    Molecular Weight:

    312.45

    Exact Mass:

    312.45

    EC Number:

    205-806-8

    UNII:

    90I02KLE8K

    NSC Number:

    92336

    DSSTox ID:

    DTXSID1022974

    Color/Form:

    Crystals from acetone + hexane|White to off-white...crystalline powder.

    ATC Code:

    G03DB01|G - Genito urinary system and sex hormones

    Characteristics
    PSA:

    34.1

    XLogP3:

    3.4

    Appearance:

    Solid

    Density:

    1.0697 (rough estimate)

    Melting Point:

    169-170 °C

    Boiling Point:

    392.36°C (rough estimate)

    Flash Point:

    172.2±25.7 °C

    Refractive Index:

    1.4900 (estimate)

    Water Solubility:

    Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent).

    Storage Conditions:

    Refrigerator

    Vapor Pressure:

    7.08X10-7 mm Hg at 25 deg C (est)

    Toxicity:

    LD50 oral in rat: > 4600mg/kg

    Specific rotation:

    D25 -484.5° (chloroform)

    Odor:

    Odorless

    Henrys Law Constant:

    Henry's Law constant = 4.65X10-8 atm-cu m/mol at 25 °C (est)

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 1.94X10-10 cu cm/molec-sec at 25 °C (est)|Ozone radical reaction rate constant = 5.26X10-17 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Specific target organ toxicity – repeated exposure, Category 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H372 Causes damage to organs through prolonged or repeated exposure

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P273 Avoid release to the environment.

    Response

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Do not store above 30 deg C.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    CRO

    Location:

    1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    3

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2006

    Company Profile

    Founded in 2006, ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

    Over the past 17 years, we have established a state-of-the-art QC/QA system aligning with ICH guidelines for pharmaceutical manufacturing. We provide our clients with high-quality products and CMC services across the entire life-cycle of drug development.


  • Inquiry History
    10 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Dydrogesterone

    1 MT Dec 16, 2024
    Canada

    Dydrogesterone

    1 KG Dec 18, 2024
    Pakistan

    Dydrogesterone

    72 KG Sep 23, 2024
    United States

    Dydrogesterone

    100 G Jan 30, 2024
    Pakistan

    Dydrogesterone

    5 KG Oct 12, 2023
    Canada

    Dydrogesterone

    100 MG May 25, 2026
    Armenia

    Dydrogesterone

    150 KG Jul 1, 2025
    India

    dydrogesterone

    1 KG Dec 17, 2024
    Lebanon

    DYDROGESTERONE

    10 KG Apr 17, 2024
    Pakistan

    dydrogesterone

    1 KG Sep 13, 2023
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