High purity Vinblastine 98% with best price cas 865-21-4 and Vinblastine raw material
1 Inquiries
865-21-4
Pharmaceutical Grade
99%
shenzhen
1kg/bag;25kg/Cardboard Drum
Yes
2200-12-31
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceVinblastine is a cytotoxic alkaloid used against various cancer types. Vinblastine inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM.
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)|Vinblastine is a Vinca Alkaloid.|Vinblastine is a natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. This agent may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca++ -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis. (NCI04)Basic Info-
Product Name:
Vinblastine
Other Name:Vincaleukoblastine;Vinblastine;1H-Indolizino[8,1-cd]carbazole,vincaleukoblastine deriv.;2H-3,7-Methanoazacycloundecino[5,4-b]indole,vincaleukoblastine deriv.;Vinblastin;VLB;Vincaleucoblastine;Vincaleucoblastin;1H-Indolizino[8,1-cd]carbazole-5-carboxylic acid,4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-,methyl ester,[3aR-[3aα,4β,5β,5aβ,9(3R*,5S*,7R*,9S*),10bR*,13aα]]-;[3aR-[3aα,4β,5β,5aβ,9(3R*,5S*,7R*,9S*),10bR*,13aα]]-Methyl 4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino[8,1-cd]carbazole-5-carboxylate;Rozevin;(+)-Vinblastine;Valban;Dimethyl(2β,3β,4β,5α,12β,19α)-15-[(5S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3,4-dicarboxylate;57-23-8;7060-58-4;1151994-97-6
CAS No.:865-21-4
Molecular Formula:C46H58N4O9
InChIKeys:InChIKey=JXLYSJRDGCGARV-CFWMRBGOSA-N
Molecular Weight:810.97
Exact Mass:810.97
EC Number:212-734-0
UNII:5V9KLZ54CY
DSSTox ID:DTXSID8021430
NCI Thesaurus Code:C930
Color/Form:Solvated needles from methanol
ATC Code:L01CA01|L - Antineoplastic and immunomodulating agents
Categories:
Characteristics-
PSA:
154.10000
XLogP3:4.18
Appearance:POWDER
Density:1.4±0.1 g/cm3
Melting Point:211-216 °C
Refractive Index:1.671
Water Solubility:Negligible
Storage Conditions:Vinblastine sulfate sterile powder, vinblastine sulfate injection, and solutions of the drug are light sensitive and must be protected from light. Vinblastine sulfate sterile powder and injection should be refrigerated at 2-8 °C. Following reconstitution of the sterile powder with bacteriostatic sodium chloride injection which contains phenol or benzyl alcohol as a preservative, solutions of the drug have a pH of 3.5-5 and are stable for 28 days when refrigerated at 2-8 °C.
Vapor Pressure:1.03X10-27 mm Hg at 25 °C (est)
Toxicity:LD50 intraperitoneal in mouse: 3120ug/kg
Specific rotation:D23 -32° (c = 0.88 in methanol)
Dissociation Constants:pKa1 = 5.4; pKa2 = 7.4
Experimental Properties:DECOMP AT 244-246 °C; CRYSTALS /VINBLASTINE DIHYDROCHLORIDE DIHYDRATE/|Hydroxyl radical reaction rate constant = 6.44X10-10 cu cm/molec-sec at 25 °C (est)|Ozone reaction rate constant = 1.13X10-17 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
-
Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
-
Payment Terms:
TT against copy of documents,100% TT in advance
-
Average lead Time:
30 days
-
Total Annual Revenue:
$2.5 million-$5 million
-
Total Employees:
11-50
-
Year of Establishment:
2023
-
-
Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
India
Vinblastine, Vincrastine & Fludarabine Phosphate
100 G Nov 1, 2024 Post an enquiry for this product
- Hot Searches
- polycaprolactam polymer registered under number 25038-54-4
- caustic soda price
- sodium hydroxide price
- retatrutide 30mg for sale
- dicalcium phosphate price
- ammounium sulfate
- polyurethane chemical suppliers
- janoshik tirzepatide
- solvent naphtha suppliers
- diethylenetriamine sds
- price of kerosene at sheetz
- buy nandrolone decanoate
More from this Seller
-
-
-
99% pure high quality raw material PVB CAS 63148-65-2 with Best Price
Pharmaceutical Grade / 99%
-
-
-
-
Cost-effective sourcing of 99% pure Vonoprazan CAS 881681-00-1 raw material
Pharmaceutical Grade / 99%
-
-
-
-
Guaranteed Smooth Customs Clearance for High-Purity Topiramate (CAS 97240-79-4) at Competitive Prices
Pharmaceutical Grade / 99%
-
-
-
-
99% pure high quality raw material 2-Deoxy-D-glucose CAS 154-17-6 with Best Price
Pharmaceutical Grade / 99%
-
-
-
-
98% pure high quality raw material 10-Hydroxycamptothecin CAS 19685-09-7 with Best Price
Pharmaceutical Grade / 98%
-