USA/AU/EU warehouse supply high quality Fluorocytosine powder CAS 2022-85-7 and Fluorocytosine
2022-85-7
Pharmaceutical Grade
99%
shenzhen
1kg/bag;25kg/Cardboard Drum
Yes
2024-05-11
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceFlucytosine (5-Fluorocytosine, 5-FC, Ancobon), a fluorinated pyrimidine analogue, is an antifungal drug.Target: antifungalFlucytosine, or 5-fluorocytosine, a fluorinated pyrimidine analogue, is a synthetic antimycotic drug. It is structurally related to the cytostatic fluorouracil and to floxuridine. It is available in oral and in some countries also in injectable form. A common brand name is Ancobon. Flucytosine was first synthesized in 1957 but its antifungal properties were discovered
Solid
Flucytosine is an organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections. It has a role as a prodrug. It is an organofluorine compound, a pyrimidone, an aminopyrimidine, a nucleoside analogue and a pyrimidine antifungal drug. It derives from a cytosine.|A fluorinated cytosine analog that is used as an antifungal agent.|Flucytosine is a Nucleoside Analog Antifungal.|Flucytosine is an antifungal agent used to treat severe infections caused by candida and cryptococcus. Flucytosine therapy can cause transient mild-to-moderate serum aminotransferase elevations and has been mentioned as a very rare cause of clinically apparent acute drug induced liver injury.|Flucytosine is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity. After penetration into the fungal cells, flucytosine is deaminated to its active metabolite 5-fluorouracil. 5-fluorouracil replaces uracil during fungal RNA synthesis, thereby inhibiting fungal protein synthesis. In addition, fluorouracil is further metabolized to 5-fluorodeoxyuridylic acid monophosphate, which inhibits thymidylate synthetase, thereby interrupting nucleotide metabolism, DNA synthesis and ultimately protein synthesis.Basic Info-
Product Name:
Flucytosine
Other Name:2(1H)-Pyrimidinone,6-amino-5-fluoro-;2(1H)-Pyrimidinone,4-amino-5-fluoro-;Cytosine,5-fluoro-;6-Amino-5-fluoro-2(1H)-pyrimidinone;5-Fluorocytosine;Flucytosine;4-Amino-5-fluoropyrimidin-2(1H)-one;5-Fluorocytosin;Flucytosin;Ro 2-9915;Fluocytosine;Ancobon;Fluorocytosine;Ancotyl;Ancotil;6-Amino-2-oxo-5-fluoropyrimidine;Alcobon;NSC 103805;4-Amino-5-fluoropyrimidin-2-ol;Toca FC
CAS No.:2022-85-7
Molecular Formula:C4H4FN3O
InChIKeys:InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N
Molecular Weight:129.09
Exact Mass:129.09
BRN:127285
EC Number:217-968-7
UNII:D83282DT06
NSC Number:759130|103805
DSSTox ID:DTXSID3023059
NCI Thesaurus Code:C501
Color/Form:White crystalline solid
ATC Code:D - Dermatologicals|J - Antiinfectives for systemic use
HScode:2933599090
Categories:
Characteristics-
PSA:
67.5
XLogP3:-1.1
Appearance:White to almost white Crystalline Powder
Density:1.7±0.1 g/cm3
Melting Point:295-297 °C (decomp)
Refractive Index:1.649
Water Solubility:H2O: 1.5g/100mL (25 ºC)
Storage Conditions:2-8°C
Vapor Pressure:4.5X10-6 mm Hg at 25 °C (est)
Toxicity:LD50 in mice (mg/kg): >2000 orally and s.c.; 1190 i.p.; 500 i.v. (Grunberg, 1963)
Odor:Odorless
PKA:3.26None
Henrys Law Constant:Henry's Law constant = 9.21X10-11 atm-cu m/mol at 25 °C (est)
Dissociation Constants:3.26|pKa1 = 3.26; pKa2 = 10.71
Collision Cross Section:118.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Aqueous solutions, both acidic and basic, are stable.|Hydroxyl radical reaction rate constant = 1.19X10-11 cu cm/molec-sec at 25 °C (est)|Ozone reaction rate constant = 7.0X10-19 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
capsules should be stored in tight, light-resistant containers at a temperature less than 40 deg C, preferably at 15-30 deg C.
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Seller Information
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Business Type:
Trader
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Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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