Chinese manufacture PNQ supply 2-Ketoglutaric acid/AKG

Name	2-Ketoglutaric acid
Synonyms	2-Oxoglutaric acid; 2-Oxopentanedioic acid ; alpha-Ketoglutaric acid
Molecular Structure
Molecular Formula	C5H6O5
Molecular Weight	146.10
CAS Registry Number	328-50-7
EINECS	206-330-3

Calcium 2-oxoglutarate, also known as calcium α-ketoglutarate or Ca(α-KG)2, is a salt formed by the combination of calcium and α-ketoglutaric acid. Here's some information about calcium 2-oxoglutarate:

1. Chemical Structure: Calcium 2-oxoglutarate has the chemical formula Ca(C5H5O5)2, representing a calcium ion (Ca^2+) bonded to two molecules of α-ketoglutarate (C5H4O5^2-). α-Ketoglutarate is an important intermediate in the citric acid cycle and plays a crucial role in cellular energy metabolism.

2. Supplemental Form: Calcium 2-oxoglutarate is commonly available as a dietary supplement in the form of capsules or powder. It is often marketed for its purported health benefits and is sometimes included in formulations targeting bone health, joint health, or exercise performance.

3. Potential Benefits: While research specifically on calcium 2-oxoglutarate is limited, α-ketoglutarate itself has been studied for its potential health effects. Some proposed benefits of α-ketoglutarate supplementation include:

   • Muscle Recovery: α-Ketoglutarate may support muscle recovery and repair after exercise by promoting protein synthesis and reducing muscle protein breakdown.
   • Exercise Performance: Some studies suggest that α-ketoglutarate supplementation may improve exercise performance, endurance, and recovery, although results are mixed.
   • Bone Health: Calcium is an essential mineral for bone health, and combining it with α-ketoglutarate in the form of calcium 2-oxoglutarate may have synergistic effects on bone density and strength.

4. Safety and Considerations: Calcium 2-oxoglutarate is generally recognized as safe (GRAS) when consumed in amounts commonly found in foods. However, as with any dietary supplement, it's important to follow recommended dosages and consult with a healthcare professional before starting supplementation, especially for individuals with pre-existing medical conditions or those taking medications.

5. Research and Clinical Studies: More research is needed to fully understand the specific health benefits and mechanisms of action of calcium 2-oxoglutarate supplementation. Clinical studies investigating its efficacy and safety in humans are limited, and further research is warranted to validate its potential therapeutic applications.

Overall, calcium 2-oxoglutarate is a compound that combines calcium with α-ketoglutarate, and while it may offer certain health benefits, more research is needed to confirm its efficacy and safety for various health conditions.