Dihexa (PNB-0408), an oligopeptide reagent, is an angiotensin IV analog with oral activity and permeability of the blood-brain barrier. Dihexa binds to Hepatocyte Chemicalbook Growth Facto with high affinity, with a Kd value of 65pM, and enhances its activity on the receptor c-Met. Dihexa has shown excellent antipsychotic activity and improved cognitive function in animal models.

How Does Dihexa Work?

Since the drug helps to form new functional synapses, it facilitates augmentation of synaptic connectivity through the newly formed synapses to treat not just memory issues but motor dysfunctions as well."

Benefits

Dihexa requires more testing and clinical trials to prove both its safety and the benefits that it can provide. As only animal testing has currently been done on the nootropic, the potential benefits of the drug are not guaranteed. The possible benefits of the nootropic drug include:

• An improvement in critical thinking- Restoration of the synapses between neurons in the nervous system
• Improved production of dopamine
• Increased mental stamina
• Enhanced articulation
• Improved circulation
• Accelerated wound healing
• An increase in musc growth
• Reduction of cognitive decline in patients with Alzheimer's disease or other degenerative cognitive diseases
• Enhanced creative thinking
• Improvement of problem-solving abilities
• Improved cardiovascular health
• Increased motivation

Side Effects

Dihexa has only been lab and animal tested, so the inherent risk factors of the drug are not widely known. Personal accounts of individuals taking the drug give some insight into the possible risks, but the overall safety of long term use is still unclear. The use of the drug short term does pose the possibility of side effects. Potential side effects include a reduced attention span, irritability, mood swings, change of taste, increased anxiety, nausea, and insomnia.

Dosages

Dose Dihexa is not approved by the FDA and there is no standard recommended dose. It is recommended to consult a healthcare provider before beginning a nootropics regimen to verify the safety of the dose for individuals. Drug manufacturers put a recommended dose of 10 mg to 20 mg per week on the package.