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Factory Price Epigallocatechin gallate CAS NO (989-51-5)

Name: Factory Price Epigallocatechin gallate CAS NO (989-51-5)
Brand: Custom
SKU: pr2404301068
Price: 100 USD
Availability: InStock

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CAS No.:

989-51-5

Grade:

Industrial Grade

Content:

99%

Port:

Durban

Brand:

Custom

Packaging:

As per customer requirement

Sample Available:

Yes

Price valid (until):

2024-05-30

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Conex Chemicals PTY Ltd

Company Type:

Distributor

Location:

South Africa

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment

Average Lead Time:

60 days

Qualification:

Main Products:

Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

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Product Details
Seller Information
Inquiry History

Description

Product Detail

1. - 1. 1. Introduction to Epigallocatechin Gallate (EGCG) (989-51-5)
        
        Epigallocatechin gallate (EGCG) is a polyphenolic compound found in green tea, known for its numerous health-promoting properties.
        
        This review aims to explore the structure, biological activities, and health benefits of EGCG.
        
        Chemical Structure
        
        EGCG belongs to the catechin class of flavonoids and is characterized by its catechol structure and galloyl moiety.
        
        It consists of four hydroxyl groups on the B ring, including the trihydroxylated structure unique to catechins, and a gallate ester on the D ring.
        
        Sources and Occurrence
        
        EGCG is abundant in green tea (Camellia sinensis) and constitutes a significant portion of its polyphenolic content.
        
        It is also found in smaller quantities in other tea varieties, such as black tea, and certain fruits, vegetables, and medicinal plants.
        
        Biological Activities
        
        EGCG exhibits a wide range of biological activities, including antioxidant, anti-inflammatory, anti-cancer, anti-obesity, and cardioprotective effects.
        
        It modulates various signaling pathways and molecular targets involved in cellular processes, contributing to its diverse pharmacological properties.
        
        Antioxidant Activity
        
        EGCG is a potent antioxidant that scavenges reactive oxygen species (ROS) and protects cells from oxidative damage.
        
        It inhibits lipid peroxidation, protein oxidation, and DNA damage, thereby mitigating oxidative stress-related pathologies.
        
        Anti-inflammatory Effects
        
        EGCG exerts anti-inflammatory effects by inhibiting pro-inflammatory mediators and signaling pathways, including NF-κB and MAPK pathways.
        
        It suppresses the production of inflammatory cytokines and chemokines, attenuating inflammation in various tissues and organs.
        
        Anti-cancer Properties
        
        EGCG possesses anti-cancer properties attributed to its ability to inhibit tumor cell proliferation, induce apoptosis, and inhibit angiogenesis and metastasis.
        
        It targets multiple signaling pathways involved in carcinogenesis, making it a promising candidate for cancer prevention and therapy.
        
        Cardioprotective Effects
        
        EGCG has cardioprotective effects by improving lipid metabolism, reducing oxidative stress, and enhancing vascular function.
        
        It lowers blood pressure, reduces cholesterol levels, and inhibits platelet aggregation, reducing the risk of cardiovascular diseases.
        
        Neuroprotective Effects
        
        EGCG exhibits neuroprotective effects by modulating neurotransmitter levels, promoting neuronal survival, and inhibiting neuroinflammation and oxidative stress.
        
        It shows potential in the prevention and treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases.
        
        Clinical Applications and Health Benefits
        
        EGCG supplementation has been studied for its potential health benefits in various conditions, including obesity, diabetes, metabolic syndrome, and neurodegenerative disorders.
        
        Clinical trials are ongoing to evaluate its efficacy, safety, and optimal dosage for the prevention and treatment of these diseases.
        
        Conclusion: Potential of EGCG in Health Promotion
        
        EGCG, as a bioactive compound abundant in green tea, offers numerous health benefits attributed to its antioxidant, anti-inflammatory, anti-cancer, cardioprotective, and neuroprotective properties.
        
        Further research is needed to elucidate its mechanisms of action, optimize its bioavailability, and translate its therapeutic potential into clinical practice for the promotion of human health and well-being.

Specifications

Items	Specifications
CAS Number	989-51-5
Chemical Formula	C22H18O11
Molecular Weight	Approximately 458.38 g/mol
Appearance	White to pale yellow crystalline powder
Purity	≥ 98%
Melting Point	230-235°C
Boiling Point	Not applicable
Density	1.91 g/cm³
Solubility	Soluble in water, ethanol, methanol
Storage	Store in a cool, dry place away from heat and moisture
Stability	Stable under normal conditions
Odor	Odorless
Applications	Used as a dietary supplement, antioxidant, and in cosmetics, pharmaceuticals, and food products

CAS Number	106-33-2
Chemical Formula	C14H28O2
Molecular Weight	Approximately 228.37 g/mol
Appearance	Colorless to pale yellow liquid
Purity	≥ 98%
Melting Point	-15 to -13°C
Boiling Point	270-273°C
Density	0.874 g/cm³
Refractive Index	1.421-1.423 at 20°C
Flash Point	111°C (closed cup)
Solubility	Insoluble in water, soluble in organic solvents
Storage	Store in a cool, dry place away from heat and moisture
Stability	Stable under normal conditions
Odor	Fruity, waxy
Applications	Flavoring agent, fragrance ingredient, solvent, intermediate in organic synthesis

Product Pictures

ECHEMI Editorial Reference

solid
Solid
(-)-epigallocatechin 3-gallate is a gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin. It has a role as an antineoplastic agent, an antioxidant, a Hsp90 inhibitor, a neuroprotective agent, a plant metabolite, a geroprotector and an apoptosis inducer. It is a gallate ester, a polyphenol and a member of flavans. It derives from a (-)-epigallocatechin.|Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.|Hydroxycut is the commercial name a variety of multi-ingredient nutritional supplements (MINS) marketed for weight loss, body building and “fat burning”. In 2004, Hydroxycut products containing ephedra were withdrawn from use in the United States because of cardiovascular risks and in 2009 because of hepatotoxicity. Nevertheless, Hydroxycut products with different ingredients are still commercially available and have continued to be implicated in cases of clinically apparent acute liver injury.|SLIMQUICK is a popular, proprietary line of multi-ingredient nutritional supplements (MINS) marketed as weight loss products and sold widely in pharmacies and grocery stores as well on the internet. The major ingredients in the products include green tea extract, caffeine and various herbal, fruit and vegetable extracts. There have been rare reports of clinically apparent liver injury in patients taking SLIMQUICK products, the majority of which had clinical features suggestive of green tea hepatotoxicity.|Epigallocatechin Gallate is a phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells. It is under study as a potential cancer chemopreventive agent. (NCI)

Basic Info

Product Name:

Epigallocatechin gallate

Other Name:

Benzoic acid,3,4,5-trihydroxy-,(2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester;Epigallocatechol,3-gallate,(-)-;Benzoic acid,3,4,5-trihydroxy-,3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester,(2R-cis)-;Epigallocatechol,3-gallate;Epigallocatechol,gallate;Gallic acid,3-ester with epigallocatechol,(-)-;(-)-Epigallocatechin gallate;(-)-Epigallocatechol gallate;(-)-Epigallocatechin 3-gallate;Epigallocatechin gallate;Epigallocatechin 3-gallate;3-O-Galloyl-(-)-epigallocatechin;(-)-Epigallocatechin 3-O-gallate;L-Epigallocatechin gallate;epi-Gallocatechin 3-O-gallate;(-)-epi-Gallocatechin 3-O-gallate;NVP-XAA 723;Epigallocatechin 3-O-gallate;Epigallocatechin-3-monogallate;Teavigo;PF-EGCg 90;EGCG;epi-Gallocatechin gallate;Theliokeep;Teafuran 90S;EGCg-OP;863-65-0;435276-52-1

CAS No.:

989-51-5

Molecular Formula:

C22H18O11

InChIKeys:

InChIKey=WMBWREPUVVBILR-WIYYLYMNSA-N

Molecular Weight:

458.37

Exact Mass:

458.37

EC Number:

479-560-7

UNII:

BQM438CTEL

DSSTox ID:

DTXSID1029889|DTXSID6020567|DTXSID0031398

NCI Thesaurus Code:

C1088

HScode:

29339900

Categories:

Plant Extracts

Characteristics

PSA:

197

XLogP3:

1.2

Appearance:

Solid

Density:

1.90±0.1 g/cm3(Predicted)

Melting Point:

217 °C

Boiling Point:

909.1°C at 760 mmHg

Flash Point:

320ºC

Refractive Index:

1.857

Water Solubility:

soluble in ethanol, dimethyl formamide, water.H2O: ≥5mg/mL, clear

Storage Conditions:

2-8°C

Toxicity:

LD50 oral in mouse: 2170mg/kg

Specific rotation:

D -185 ±2°(ethanol)

Collision Cross Section:

206.1 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Epigallocatechin gallate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin sensitization, Category 1

Eye irritation, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H317 May cause an allergic skin reaction H319 Causes serious eye irritation H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Epigallocatechin gallate Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

Location:
13 PROTEA PARK MILKWOOD STREET RANGEVIEW GAUTENG 1739

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment

Average lead Time:
60 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2012

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Epigallocatechin Gallate	1 KG	May 8, 2026

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Factory Price Epigallocatechin gallate CAS NO (989-51-5)

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