Skin sensitization, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

no data available

If inhaled

Following skin contact

Following eye contact

Following ingestion

SYMPTOMS: Symptoms of exposure to this compound may include allergic contact dermatitis. Skin contact may also lead to sensitization. Eye contact can cause irritation. ACUTE/CHRONIC HAZARDS: This compound may be harmful by inhalation, ingestion or skin absorption. It is very irritating to the eyes. When heated to decomposition or upon contact with acid or acid fumes, it emits highly toxic fumes of carbon monoxide, carbon dioxide, sulfur oxides and nitrogen oxides. (NTP, 1992)

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Aromatic hydrocarbons and related compounds

Suitable extinguishing media: Use water spray, alchohol-resistant foam, dry chemical or carbon dioxide.

This chemical is combustible. (NTP, 1992)

Use water spray, dry powder, foam, carbon dioxide.

Personal protection: face shield and particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Personal precautions, protective equipment and emergency procedure: Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Avoid breathing dust.

NO open flames. PREVENT DISPERSION OF DUST. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Separated from acids.Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place.

Occupational Exposure limit values

Biological limit values

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

Decomposes on burning. This produces toxic and irritating fumes (sulfur oxides, nitrogen oxides). Reacts with acids and acid fumes. This produces toxic and irritating fumes (sulfur oxides, nitrogen oxides).

no data available

2-MERCAPTOBENZOTHIAZOLE is incompatible with strong oxidizing agents. Also incompatible with acids and acid fumes (NTP, 1992).

no data available

on contact with acid or acid fumes it emits toxic /oxides of sulfur and oxides of nitrogen/.

When heated to decomp ... it emits toxic /oxides of sulfur and oxides of nitrogen/.

Acute toxicity

• Oral: LD50 - rat (male/female) - 3 800 mg/kg bw. Remarks:Clinical signs: reduced appetite and activity, increased weakness, collapse and death.
• Inhalation: LC50 - rat (male/female) - > 1 270 mg/L air.
• Dermal: LD50 - rabbit (male/female) - > 7 940 mg/kg bw.

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 0.73 mg/L - 96 h.
• Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 0.71 mg/L - 48 h.
• Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 0.5 mg/L - 72 h.
• Toxicity to microorganisms: EC50 - activated sludge - 3 301 mg/L - 3 h. Remarks:Respiration rate.

AEROBIC: Several biodegradation studies with 2-mercaptobenzothiazole using an activated sludge seed inoculum indicate little or no biodegration(1-4). 2-Mercaptobenzothiazole, present at 100 mg/L, reached only 2.5% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test indicating the compound is not readily biodegradable(1). It has been suggested that at the concentrations used in these studies, 56-100 ppm, 2-mercaptobenzothiazole is toxic to the microorganisms in the sludge(5). A more detailed study indicated that inhibitory effects occur between 20 and 50 ppm of 2-mercaptobenzothiazole(5). When the sludge is well acclimated and the concentrations low enough, 2-mercaptobenzothiazole may completely biodegrade forming 2-benzothiazolesulfonate or dibenzothiazole-2,2-disulfide, depending on conditions(5). In a screening test comparable to OECD Method 301B (CO2 evolution), 2-mercaptobenzothiazole, present at 17-18 mg/L, reached only 1-5% degradation after 35 days of incubation which classified the compound as not inherently biodegradable(6). Another CO2 evolution study determined <1% degradation after 28 days using adapted activated sludge and an initial 2-mercaptobenzothiazole concentration of 23.8 mg/L(6). Partial degradation of 2-mercaptobenzothiazole was found in laboratory-scale fed-batch systems using activated sludge inoculum taken from rubber chemicals wastewater treatment plants(6).

A BCF of <8 was measured in fish for 2-mercaptobenzothiazole(SRC), using carp (Cyprinus carpio) which were exposed over a 6-week period(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of 2-mercaptobenzothiazole was measured as 677, 326 and 1360 in California sandy loam, California clay loam and California sandy soil respectively(1). The Koc of 2-mercaptobenzothiazole was measured as 2130, 3560 and 2590 in three different sediments(1). The Koc of 2-mercaptobenzothiazole was measured as 915, 863, 1429 and 1829 in Drummer silty clay loam, Spinks sandy loam, Ray silt loam and Lintonia sandy loam soil respectively(1). According to a classification scheme(2), these estimated Koc values suggest that 2-mercaptobenzothiazole is expected to have moderate to slight mobility in soil. The pKa of 2-mercaptobenzothiazole is 7.03(1), indicating that this compound will exist partially in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(3).

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%