Fleroxacin CAS79660-72-3 White to yellowish crystalline powder
79660-72-3
Pharmaceutical grade
99%
QINGDAO
AIRUIKE
25kg/Cardboard Drum
2025-10-10
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceFleroxacin is a broad-spectrum antimicrobial fluoroquinolone.Target: AntibacterialFleroxacin (Ro 23-6240; AM-833) is a new trifluorinated quinolone exhibiting high activity against a broad spectrum of gram-negative and gram-positive bacteria. Fleroxacin is characterized pharmacokinetically by a long elimination half-life (9 to 10 h) and high concentrations in plasma (e.g., maximum concentration of 2.3 micrograms/ml after an oral dose of 200 mg) [1]. Fleroxacin is effective against Haemop
Fleroxacin is a fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria. It has a role as a topoisomerase IV inhibitor, an antibacterial drug and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. It is a member of quinolines, a fluoroquinolone antibiotic, a difluorobenzene, a N-alkylpiperazine and a monocarboxylic acid.|Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Fleroxacin is not an inhibitor of CYP1A2.|A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.Basic Info-
Product Name:
Fleroxacin
Other Name:3-Quinolinecarboxylic acid,6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-;6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;Ro 23-6240;AM 833;Fleroxacin;Megalocin;Flerofloxacin;Quinodis;Ro 23-6240/000;Megalone;110158-59-3;407610-62-2
CAS No.:79660-72-3
Molecular Formula:C17H18F3N3O3
InChIKeys:InChIKey=XBJBPGROQZJDOJ-UHFFFAOYSA-N
Molecular Weight:369.34
Exact Mass:369.34
EC Number:1312995-182-4
UNII:N804LDH51K
DSSTox ID:DTXSID1046714
ATC Code:J - Antiinfectives for systemic use
HScode:2933990090
Categories:
Characteristics-
PSA:
64.1
XLogP3:0.24
Appearance:white to off-white
Density:1.4±0.1 g/cm3
Melting Point:270 °C (decomp)
Boiling Point:535.3±50.0 °C at 760 mmHg
Flash Point:277.6±30.1 °C
Refractive Index:1.568
Water Solubility:0.1 M NaOH: soluble 10mg/mL
Storage Conditions:2-8°C
Collision Cross Section:189.8 Ų [M+H]+ [CCS Type: TW, Method: calibrated with Waters Major Mix]|198.8 Ų [M+Na]+ [CCS Type: TW, Method: calibrated with Waters Major Mix]
Hazard IdentificationClassification of the substance or mixture
Specific target organ toxicity â single exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H371 May cause damage to organs
Precautionary statement(s) Prevention P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P308+P316 IF exposed or concerned: Get emergency medical help immediately.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
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Certifications:
Credit rating certificate,Hazardous Chemicals Business License
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
