ETC-1002 cas738606-46-7 The best price
7 Inquiries
738606-46-7
Pharmaceutical grade
99%
qingdao
AIRUIKE
25kg/Cardboard Drum
2025-10-10
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceBempedoic acid is an alpha,omega-dicarboxylic acid that is pentadecanedioic acid which is substituted by methyl groups groups at positions 2 and 14, and by a hydroxy group at position 8. It is a drug used for the treatment of high LDL cholesterol, which is sometimes referred to as 'bad cholesterol'. It has a role as an antilipemic drug, an EC 2.3.3.8 (ATP citrate synthase) inhibitor and a prodrug.|High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. Caused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are insufficiently managed with maximally tolerated statin therapy alone, requiring additional treatment for hypercholesterolemia. Bempedoic acid is first-in-class adenosine triphosphate-citrate lyase (ACL) inhibitor used once a day for reducing LDL cholesterol levels in statin-refractory patients. It was developed by Esperion Therapeutics Inc. and approved by the FDA on February 21, 2020. A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous statin treatment.|Bempedoic acid is an Adenosine Triphosphate-Citrate Lyase Inhibitor. The mechanism of action of bempedoic acid is as an Adenosine Triphosphate-Citrate Lyase Inhibitor.Basic Info
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Product Name:
ETC 1002
Other Name:Pentadecanedioic acid,8-hydroxy-2,2,14,14-tetramethyl-;8-Hydroxy-2,2,14,14-tetramethylpentadecanedioic acid;ESP 55016;ETC 1002;Bempedoic acid;Nilemdo;Nexletol
CAS No.:738606-46-7
Molecular Formula:C19H36O5
InChIKeys:InChIKey=HYHMLYSLQUKXKP-UHFFFAOYSA-N
Molecular Weight:344.49
Exact Mass:344.49
UNII:1EJ6Z6Q368
ATC Code:C10AX|C10B|C - Cardiovascular system
Categories:
Characteristics-
PSA:
94.8
XLogP3:4.8
Density:1.045±0.06 g/cm3(Predicted)
Melting Point:87-92
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Specific target organ toxicity â repeated exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P319 Get medical help if you feel unwell.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
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Certifications:
Credit rating certificate,Hazardous Chemicals Business License
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Inquiry History7 Inquiries
Country Product Purchase Quantity Date Posted
India
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250 G Apr 11, 2024
India
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600.00 KG Oct 21, 2025
India
Bempedoic acid
600 KG Oct 17, 2025
India
Bempedoic acid
1.00 KG Oct 23, 2024
India
Bempedoic acid
1.00 KG Oct 22, 2024 Post an enquiry for this product