cas3562-63-8 Megestrol
3562-63-8
Pharmaceutical Grade
99%
SHANGHAI
airuike
25kg/Cardboard Drum
Yes
2025-06-20
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceMegestrol is a synthetic progestin and used for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis[1].
Megestrol is a 3-oxo Delta(4)-steroid that is pregna-4,6-diene-3,20-dione substituted by a methyl group at position 6 and a hydroxy group at position 17. It has a role as a contraceptive drug, an antineoplastic agent, an appetite enhancer, a progestin and a synthetic oral contraceptive. It is a 20-oxo steroid, a 17alpha-hydroxy steroid, a 3-oxo-Delta(4) steroid and a tertiary alpha-hydroxy ketone.|Megestrol is a Progestin.|Megestrol is a synthetic derivative of progesterone with antiestrogenic activity. Megestrol binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. In addition, megestrol stimulates appetite in cachectic subjects.|A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.Basic Info-
Product Name:
Megestrol
Other Name:Pregna-4,6-diene-3,20-dione,17-hydroxy-6-methyl-;17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione;Megestrol;magestrol
CAS No.:3562-63-8
Molecular Formula:C22H30O3
InChIKeys:InChIKey=VXIMPSPISRVBPZ-NWUMPJBXSA-N
Molecular Weight:342.47
Exact Mass:342.47
EC Number:222-628-6
UNII:EA6LD1M70M
NCI Thesaurus Code:C630
ATC Code:L02AB01|G - Genito urinary system and sex hormones|L - Antineoplastic and immunomodulating agents
Categories:
Characteristics-
PSA:
54.4
XLogP3:3.41 (est)
Density:1.2±0.1 g/cm3
Melting Point:207-208 °C @ Solvent: Diethyl ether, Acetone
Boiling Point:500.4±50.0 °C at 760 mmHg
Flash Point:270.5±26.6 °C
Refractive Index:1.569
Water Solubility:In water, 27 mg/L at 25 deg C (est)
Storage Conditions:Megestrol acetate tablets should be stored in well-closed containers at a temperature less than 40 deg C, preferably between 15-30 deg C and megestrol acetate oral suspension should be stored in tight containers at a temperature of 25 deg C or less.
Vapor Pressure:3.48X10-10 mm Hg at 25 deg C (est)
Odor:Odorless
Taste:Tasteless
Henrys Law Constant:Henry's Law constant = 1.14X10-8 atm-cu m/mol at 25 °C (est)
Collision Cross Section:202.21 Ų [M+Cl]-
Experimental Properties:Crystals. MW: 384.50, mp 214-216 °C. Soluble in water. /Megestrol acetate/|Hydroxyl radical reaction rate constant = 2.55X10-10 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Megestrol acetate tablets should be stored in well-closed containers at a temperature less than 40 deg C, preferably between 15-30 deg C and megestrol acetate oral suspension should be stored in tight containers at a temperature of 25 deg C or less.
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
Company Certificates-
Credit rating certificate
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Hazardous Chemicals Business License
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