EGT1442 cas 1118567-05-7
6 Inquiries
1118567-05-7
Analytical Reagent
99%
qingdao
AIRUIKE
1kg
2024-07-17
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceBexagliflozin is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively.target: SGLT2IC50: 5.6 μM (SGLT1)/ 2 nM (SGLT2)1) In normal rats and dogs a saturable urinary glucose excretion was produced with an ED50 of 0.38 and 0.09 mg/kg, respectively.2) EGT1442 significantly prolonged the median survival of SHRSP rats.3) EGT1442 dose-dependently reduced HbA1c and blood glucose concentration without affecting body mass or insulin level.
Bexagliflozin is under investigation for the treatment of Type 2 Diabetes Mellitus. Bexagliflozin has been investigated for the treatment of Diabetes Mellitus and Type2 Diabetes Mellitus.Basic Info-
Product Name:
EGT1442
Other Name:(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;bexagliflozin;UNII-EY00JF42FV;EGT-1442;EGT1442;Bexagliflozin [USAN];THR-1442;EGT0001442;EY00JF42FV
CAS No.:1118567-05-7
Molecular Formula:C24H29ClO7
InChIKeys:BTCRKOKVYTVOLU-SJSRKZJXSA-N
Molecular Weight:464.9 g/mol
Exact Mass:464.160187
UNII:EY00JF42FV
Categories:
Characteristics-
PSA:
109 Ų
XLogP3:2.00350
Density:1.41
Boiling Point:671.0±55.0 °C(Predicted)
Flash Point:359.6±31.5 °C
Refractive Index:1.642
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
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Certifications:
Credit rating certificate,Hazardous Chemicals Business License
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Inquiry History6 Inquiries
Country Product Purchase Quantity Date Posted
Brazil
Bexaglifozin
250 G Jan 13, 2025
Bangladesh
EGT1442
200 KG Nov 13, 2023
Pakistan
Bexagliflozin
10 G Feb 19, 2025
Bangladesh
Bexagliflozin
1.00 KG Nov 11, 2023
Pakistan
Bexagliflozin
1 MT Oct 24, 2025
India
Bexagliflozin
5 G Mar 24, 2025 Post an enquiry for this product